X-RAY STRUCTURAL STUDIES OF ANTIBIOTIC MATERIALS

  • RICHARD JAMES GIRVEN

Student thesis: PhD

Abstract

Optimum conditions were devised for the crystallisation of a number of antibiotic s of pharmaceutical interest, and related compounds of particular significance in structure activity investigations. Single crystal X-ray analysis techniques were then used for the determination of the structures of two ß- lactam compounds and an analgesic compound of unusually low physical dependence liability.
Date of Award1977
Original languageEnglish
Awarding Institution
  • University of Plymouth

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