Yeast central nervous system infection in a critically ill patient: A case report

Frantzeska Frantzeskaki*, Chryssi Diakaki, Michalis Rizos, Maria Theodorakopoulou, Panagiotis Papadopoulos, Anastasia Antonopoulou, Nikitas Nikitas, Michail Lignos, Elias Brountzos, Aristea Velegraki, Elisabeth Paramythiotou, John Panagyotides, Apostolos Armaganidis, George Dimopoulos

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction. Invasive fungal infections are alarmingly common in intensive care unit patients; invasive fungal infections are associated with increased morbidity and mortality. Risk factors are the increased use of indwelling central venous catheters, the use of broad spectrum antibiotics, parenteral nutrition, renal replacement therapy and immunosuppression. Diagnosis of these infections might be complicated, requiring tissue cultures. In addition, therapy of invasive fungal infections might be difficult, given the rising resistance of fungi to antifungal agents. Case presentation. We describe the case of a 28-year-old Greek man with yeast central nervous system infection. Conclusions: Difficult-to-treat fungal infections may complicate the clinical course of critically ill patients and render their prognosis unfavorable. This report presents a case that was rare and difficult to treat, along with a thorough review of the investigation and treatment of these kinds of fungal infections in critically ill patients.

Original languageEnglish
Article number253
JournalJournal of Medical Case Reports
Volume8
Issue number1
DOIs
Publication statusPublished - 15 Jul 2014
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

Keywords

  • Emerging fungal infections
  • ICU patients
  • Treatment

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