Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1

Ana Valencia; Candelaria Vergara; Chloe L. Thio; Nicolas Vince; Venceslas Douillard; Alba Grifoni; Andrea L. Cox; Eric O. Johnson; Alex H. Kral; James J. Goedert; Alessandra Mangia; Valeria Piazzolla; Shruti H. Mehta; Gregory D. Kirk; Arthur Y. Kim; Georg M. Lauer; Raymond T. Chung; Jennifer C. Price; Salim I. Khakoo; Laurent Alric; Matthew E. Cramp; Sharyne M. Donfield; Brian R. Edlin; Michael P. Busch; Graeme Alexander; Hugo R. Rosen; Edward L. Murphy; Genevieve L. Wojcik; Mary Carrington; Pierre Antoine Gourraud; Alessandro Sette; David L. Thomas; Priya Duggal

doi:10.1016/j.ajhg.2022.01.001

Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1

Ana Valencia
, Candelaria Vergara
, Chloe L. Thio
, Nicolas Vince
, Venceslas Douillard
, Alba Grifoni
, Andrea L. Cox
, Eric O. Johnson
, Alex H. Kral
, James J. Goedert
, Alessandra Mangia
, Valeria Piazzolla
, Shruti H. Mehta
, Gregory D. Kirk
, Arthur Y. Kim
, Georg M. Lauer
, Raymond T. Chung
, Jennifer C. Price
, Salim I. Khakoo
, Laurent Alric

Matthew E. Cramp, Sharyne M. Donfield, Brian R. Edlin, Michael P. Busch, Graeme Alexander, Hugo R. Rosen, Edward L. Murphy, Genevieve L. Wojcik, Mary Carrington, Pierre Antoine Gourraud, Alessandro Sette, David L. Thomas, Priya Duggal^*

^*Corresponding author for this work

Peninsula Medical School

Johns Hopkins University
Universidad Pontificia Bolivariana
Université de Nantes
La Jolla Institute for Allergy and Immunology
RTI International
National Institutes of Health
IRCCS Ospedale Casa Sollievo della Sofferenza - San Giovanni Rotondo (FG)
Harvard University
University of California at San Francisco
University of Southampton
Toulouse University
South West Liver Unit
Rho, Inc.
SUNY Downstate College of Medicine
The Royal Free Hospital
University of Colorado Anschutz Medical Campus
Massachusetts Institute of Technology
University of California at San Diego

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	299-310
Number of pages	0
Journal	The American Journal of Human Genetics
Volume	109
Issue number	2
DOIs	https://doi.org/10.1016/j.ajhg.2022.01.001
Publication status	Published - Feb 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/j.ajhg.2022.01.001

Cite this

Valencia, A., Vergara, C., Thio, C. L., Vince, N., Douillard, V., Grifoni, A., Cox, A. L., Johnson, E. O., Kral, A. H., Goedert, J. J., Mangia, A., Piazzolla, V., Mehta, S. H., Kirk, G. D., Kim, A. Y., Lauer, G. M., Chung, R. T., Price, J. C., Khakoo, S. I., ... Duggal, P. (2022). Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1. The American Journal of Human Genetics, 109(2), 299-310. https://doi.org/10.1016/j.ajhg.2022.01.001

@article{4878834d581f417ab0470a137ffc7772,

title = "Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1",

author = "Ana Valencia and Candelaria Vergara and Thio, \{Chloe L.\} and Nicolas Vince and Venceslas Douillard and Alba Grifoni and Cox, \{Andrea L.\} and Johnson, \{Eric O.\} and Kral, \{Alex H.\} and Goedert, \{James J.\} and Alessandra Mangia and Valeria Piazzolla and Mehta, \{Shruti H.\} and Kirk, \{Gregory D.\} and Kim, \{Arthur Y.\} and Lauer, \{Georg M.\} and Chung, \{Raymond T.\} and Price, \{Jennifer C.\} and Khakoo, \{Salim I.\} and Laurent Alric and Cramp, \{Matthew E.\} and Donfield, \{Sharyne M.\} and Edlin, \{Brian R.\} and Busch, \{Michael P.\} and Graeme Alexander and Rosen, \{Hugo R.\} and Murphy, \{Edward L.\} and Wojcik, \{Genevieve L.\} and Mary Carrington and Gourraud, \{Pierre Antoine\} and Alessandro Sette and Thomas, \{David L.\} and Priya Duggal",

year = "2022",

month = feb,

doi = "10.1016/j.ajhg.2022.01.001",

language = "English",

volume = "109",

pages = "299--310",

journal = "The American Journal of Human Genetics",

issn = "0002-9297",

publisher = "Cell Press",

number = "2",

}

Valencia, A, Vergara, C, Thio, CL, Vince, N, Douillard, V, Grifoni, A, Cox, AL, Johnson, EO, Kral, AH, Goedert, JJ, Mangia, A, Piazzolla, V, Mehta, SH, Kirk, GD, Kim, AY, Lauer, GM, Chung, RT, Price, JC, Khakoo, SI, Alric, L, Cramp, ME, Donfield, SM, Edlin, BR, Busch, MP, Alexander, G, Rosen, HR, Murphy, EL, Wojcik, GL, Carrington, M, Gourraud, PA, Sette, A, Thomas, DL & Duggal, P 2022, 'Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1', The American Journal of Human Genetics, vol. 109, no. 2, pp. 299-310. https://doi.org/10.1016/j.ajhg.2022.01.001

TY - JOUR

T1 - Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1

AU - Valencia, Ana

AU - Vergara, Candelaria

AU - Thio, Chloe L.

AU - Vince, Nicolas

AU - Douillard, Venceslas

AU - Grifoni, Alba

AU - Cox, Andrea L.

AU - Johnson, Eric O.

AU - Kral, Alex H.

AU - Goedert, James J.

AU - Mangia, Alessandra

AU - Piazzolla, Valeria

AU - Mehta, Shruti H.

AU - Kirk, Gregory D.

AU - Kim, Arthur Y.

AU - Lauer, Georg M.

AU - Chung, Raymond T.

AU - Price, Jennifer C.

AU - Khakoo, Salim I.

AU - Alric, Laurent

AU - Cramp, Matthew E.

AU - Donfield, Sharyne M.

AU - Edlin, Brian R.

AU - Busch, Michael P.

AU - Alexander, Graeme

AU - Rosen, Hugo R.

AU - Murphy, Edward L.

AU - Wojcik, Genevieve L.

AU - Carrington, Mary

AU - Gourraud, Pierre Antoine

AU - Sette, Alessandro

AU - Thomas, David L.

AU - Duggal, Priya

PY - 2022/2

Y1 - 2022/2

U2 - 10.1016/j.ajhg.2022.01.001

DO - 10.1016/j.ajhg.2022.01.001

M3 - Article

SN - 0002-9297

VL - 109

SP - 299

EP - 310

JO - The American Journal of Human Genetics

JF - The American Journal of Human Genetics

IS - 2

ER -