The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline

E. O. Thomas; A. Manara; R. A. Dineen; A. Mortimer; O. Aziz; P. Dean; P. Elliott; D. M. Summers; P. C. Whitfield; P. J. Hutchinson; D. Gardiner

doi:10.1111/anae.15950

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline

E. O. Thomas^*, A. Manara, R. A. Dineen, A. Mortimer, O. Aziz, P. Dean, P. Elliott, D. M. Summers, P. C. Whitfield, P. J. Hutchinson, D. Gardiner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

This multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurological criteria. A multidisciplinary panel reviewed the literature and UK practice in the diagnosis of death using neurological criteria and recommended cerebral CT angiography as the ancillary investigation of choice when death cannot be confirmed by clinical criteria alone. Cerebral CT angiography has been shown to have 100% specificity in supporting a diagnosis of death using neurological criteria and is an investigation available in all acute hospitals in the UK. A standardised technique for performing the investigation is described alongside a reporting template. The panel were unable to make recommendations for ancillary testing in children or patients receiving extracorporeal membrane oxygenation.

Original language	English
Pages (from-to)	330-336
Number of pages	7
Journal	Anaesthesia
Volume	78
Issue number	3
DOIs	https://doi.org/10.1111/anae.15950
Publication status	Published - Mar 2023
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Keywords

brain death
brain death testing
CT angiography
diagnosis of death
intensive care medicine

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10.1111/anae.15950

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Thomas, E. O., Manara, A., Dineen, R. A., Mortimer, A., Aziz, O., Dean, P., Elliott, P., Summers, D. M., Whitfield, P. C., Hutchinson, P. J., & Gardiner, D. (2023). The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline. Anaesthesia, 78(3), 330-336. https://doi.org/10.1111/anae.15950

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title = "The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline",

abstract = "This multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurological criteria. A multidisciplinary panel reviewed the literature and UK practice in the diagnosis of death using neurological criteria and recommended cerebral CT angiography as the ancillary investigation of choice when death cannot be confirmed by clinical criteria alone. Cerebral CT angiography has been shown to have 100% specificity in supporting a diagnosis of death using neurological criteria and is an investigation available in all acute hospitals in the UK. A standardised technique for performing the investigation is described alongside a reporting template. The panel were unable to make recommendations for ancillary testing in children or patients receiving extracorporeal membrane oxygenation.",

keywords = "brain death, brain death testing, CT angiography, diagnosis of death, intensive care medicine",

author = "Thomas, {E. O.} and A. Manara and Dineen, {R. A.} and A. Mortimer and O. Aziz and P. Dean and P. Elliott and Summers, {D. M.} and Whitfield, {P. C.} and Hutchinson, {P. J.} and D. Gardiner",

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year = "2023",

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doi = "10.1111/anae.15950",

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pages = "330--336",

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Thomas, EO, Manara, A, Dineen, RA, Mortimer, A, Aziz, O, Dean, P, Elliott, P, Summers, DM, Whitfield, PC, Hutchinson, PJ & Gardiner, D 2023, 'The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline', Anaesthesia, vol. 78, no. 3, pp. 330-336. https://doi.org/10.1111/anae.15950

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T2 - a consensus guideline

AU - Thomas, E. O.

AU - Manara, A.

AU - Dineen, R. A.

AU - Mortimer, A.

AU - Aziz, O.

AU - Dean, P.

AU - Elliott, P.

AU - Summers, D. M.

AU - Whitfield, P. C.

AU - Hutchinson, P. J.

AU - Gardiner, D.

PY - 2023/3

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KW - brain death

KW - brain death testing

KW - CT angiography

KW - diagnosis of death

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The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline

Abstract

ASJC Scopus subject areas

Keywords

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