Abstract
<jats:p>The pattern of conduction block induced in cat peripheral nerve by compression has been investigated electrophysiologically by recording unitary action potentials. A degree of compression, associated with chronic compression disorders in man, was applied to the cat sciatic nerve and resulted in a conduction block typified by early failure of the slow conducting myelinated axons. By contrast, a greater degree of compression, a degree more likely to result in acute compression lesions, produced a different pattern of effect, inducing early conduction failure in the fast conducting myelinated axons. These results are related to earlier studies which have shown that nerve deformation during compression has a differential action upon fast myelinated axons, while nerve ischaemia has a differential action upon slow myelinated axons.</jats:p>
Original language | English |
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Pages (from-to) | 583-592 |
Number of pages | 0 |
Journal | Experimental Physiology |
Volume | 79 |
Issue number | 4 |
DOIs | |
Publication status | Published - Jul 1994 |