Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Marco Carbone; Alessandra Nardi; Steve Flack; Guido Carpino; Nikoletta Varvaropoulou; Caius Gavrila; Ann Spicer; Jonathan Badrock; Francesca Bernuzzi; Vincenzo Cardinale; Holly F. Ainsworth; Michael A. Heneghan; Douglas Thorburn; Andrew Bathgate; R Jones; James M. Neuberger; Pier Maria Battezzati; Massimo Zuin; Simon Taylor-Robinson; Maria F. Donato; John Kirby; Robert Mitchell-Thain; Annarosa Floreani; Fotios Sampaziotis; Luigi Muratori; Domenico Alvaro; Marco Marzioni; Luca Miele; Fabio Marra; Edoardo Giannini; Eugenio Gaudio; Vincenzo Ronca; Giulia Bonato; Laura Cristoferi; Federica Malinverno; Alessio Gerussi; Deborah D. Stocken; Heather J. Cordell; Gideon M. Hirschfield; Graeme J. Alexander; Richard N. Sandford; DE Jones; Pietro Invernizzi; George F. Mells; Caradog Thomas; Meshbah Rahman; Tom Yapp; Ch'ng C Lye; Melanie Harrison; R Sturgess; R Galaska; C Healey; J Whiteman; M Czaijkowski; C Gray; A Gunasekera; P Gyawli; P Premchand; S Mann; K Elliott; K Kapur; A Watson; G Foster; P Trembling; J Subhani; R Harvey; R McCorry; C Adgey; L Hobson; C Mulvaney-Jones; R Evans; T Mathialahan; D Ramanaden; J Gasem; Duyvenvoorde G Van; C Shorrock; K Seward; P Southern; J Tibble; R Penn; D Gorard; J Maiden; R Damant; A Palegwala; S Jones; Graeme J. Alexander; Matthew M

doi:10.1016/s2468-1253(18)30163-8

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Marco Carbone^*
, Alessandra Nardi
, Steve Flack
, Guido Carpino
, Nikoletta Varvaropoulou
, Caius Gavrila
, Ann Spicer
, Jonathan Badrock
, Francesca Bernuzzi
, Vincenzo Cardinale
, Holly F. Ainsworth
, Michael A. Heneghan
, Douglas Thorburn
, Andrew Bathgate
, R Jones
, James M. Neuberger
, Pier Maria Battezzati
, Massimo Zuin
, Simon Taylor-Robinson
, Maria F. Donato

John Kirby, Robert Mitchell-Thain, Annarosa Floreani, Fotios Sampaziotis, Luigi Muratori, Domenico Alvaro, Marco Marzioni, Luca Miele, Fabio Marra, Edoardo Giannini, Eugenio Gaudio, Vincenzo Ronca, Giulia Bonato, Laura Cristoferi, Federica Malinverno, Alessio Gerussi, Deborah D. Stocken, Heather J. Cordell, Gideon M. Hirschfield, Graeme J. Alexander, Richard N. Sandford, DE Jones, Pietro Invernizzi, George F. Mells, Caradog Thomas, Meshbah Rahman, Tom Yapp, Ch'ng C Lye, Melanie Harrison, R Sturgess, R Galaska, C Healey, J Whiteman, M Czaijkowski, C Gray, A Gunasekera, P Gyawli, P Premchand, S Mann, K Elliott, K Kapur, A Watson, G Foster, P Trembling, J Subhani, R Harvey, R McCorry, C Adgey, L Hobson, C Mulvaney-Jones, R Evans, T Mathialahan, D Ramanaden, J Gasem, Duyvenvoorde G Van, C Shorrock, K Seward, P Southern, J Tibble, R Penn, D Gorard, J Maiden, R Damant, A Palegwala, S Jones, Graeme J. Alexander, M

^*Corresponding author for this work

Peninsula Medical School

University of Cambridge
University of Milan - Bicocca
University of Rome Tor Vergata
Foro Italico University of Rome
I.C. Antonio Rosmini
University of Rome La Sapienza
Newcastle University
King's College Hospital NHS Foundation Trust
Royal Free London NHS Foundation Trust
University of Edinburgh
University Hospitals Birmingham NHS Foundation Trust
Ospedale San Paolo
Imperial College London
University of Milan
PBC Foundation
University of Padua
University of Bologna
Marche Polytechnic University
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
University of Florence
IRCCS Ospedale Policlinico San Martino
University of Birmingham

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	626-634
Journal	The Lancet Gastroenterology and Hepatology
Volume	3
Issue number	9
DOIs	https://doi.org/10.1016/s2468-1253(18)30163-8
Publication status	Published - Sept 2018

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10.1016/s2468-1253(18)30163-8

Cite this

Carbone, M., Nardi, A., Flack, S., Carpino, G., Varvaropoulou, N., Gavrila, C., Spicer, A., Badrock, J., Bernuzzi, F., Cardinale, V., Ainsworth, H. F., Heneghan, M. A., Thorburn, D., Bathgate, A., Jones, R., Neuberger, J. M., Battezzati, P. M., Zuin, M., Taylor-Robinson, S., ... M (2018). Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score. The Lancet Gastroenterology and Hepatology, 3(9), 626-634. https://doi.org/10.1016/s2468-1253(18)30163-8

@article{725b36db75c54343a5eb598aa3c9520f,

title = "Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score",

author = "Marco Carbone and Alessandra Nardi and Steve Flack and Guido Carpino and Nikoletta Varvaropoulou and Caius Gavrila and Ann Spicer and Jonathan Badrock and Francesca Bernuzzi and Vincenzo Cardinale and Ainsworth, \{Holly F.\} and Heneghan, \{Michael A.\} and Douglas Thorburn and Andrew Bathgate and R Jones and Neuberger, \{James M.\} and Battezzati, \{Pier Maria\} and Massimo Zuin and Simon Taylor-Robinson and Donato, \{Maria F.\} and John Kirby and Robert Mitchell-Thain and Annarosa Floreani and Fotios Sampaziotis and Luigi Muratori and Domenico Alvaro and Marco Marzioni and Luca Miele and Fabio Marra and Edoardo Giannini and Eugenio Gaudio and Vincenzo Ronca and Giulia Bonato and Laura Cristoferi and Federica Malinverno and Alessio Gerussi and Stocken, \{Deborah D.\} and Cordell, \{Heather J.\} and Hirschfield, \{Gideon M.\} and Alexander, \{Graeme J.\} and Sandford, \{Richard N.\} and DE Jones and Pietro Invernizzi and Mells, \{George F.\} and Caradog Thomas and Meshbah Rahman and Tom Yapp and Lye, \{Ch'ng C\} and Melanie Harrison and R Sturgess and R Galaska and C Healey and J Whiteman and M Czaijkowski and C Gray and A Gunasekera and P Gyawli and P Premchand and S Mann and K Elliott and K Kapur and A Watson and G Foster and P Trembling and J Subhani and R Harvey and R McCorry and C Adgey and L Hobson and C Mulvaney-Jones and R Evans and T Mathialahan and D Ramanaden and J Gasem and Van, \{Duyvenvoorde G\} and C Shorrock and K Seward and P Southern and J Tibble and R Penn and D Gorard and J Maiden and R Damant and A Palegwala and S Jones and Alexander, \{Graeme J.\} and M",

year = "2018",

month = sep,

doi = "10.1016/s2468-1253(18)30163-8",

language = "English",

volume = "3",

pages = "626--634",

journal = "The Lancet Gastroenterology and Hepatology",

issn = "2468-1253",

publisher = "Elsevier Ltd.",

number = "9",

}

Carbone, M, Nardi, A, Flack, S, Carpino, G, Varvaropoulou, N, Gavrila, C, Spicer, A, Badrock, J, Bernuzzi, F, Cardinale, V, Ainsworth, HF, Heneghan, MA, Thorburn, D, Bathgate, A, Jones, R, Neuberger, JM, Battezzati, PM, Zuin, M, Taylor-Robinson, S, Donato, MF, Kirby, J, Mitchell-Thain, R, Floreani, A, Sampaziotis, F, Muratori, L, Alvaro, D, Marzioni, M, Miele, L, Marra, F, Giannini, E, Gaudio, E, Ronca, V, Bonato, G, Cristoferi, L, Malinverno, F, Gerussi, A, Stocken, DD, Cordell, HJ, Hirschfield, GM, Alexander, GJ, Sandford, RN, Jones, DE, Invernizzi, P, Mells, GF, Thomas, C, Rahman, M, Yapp, T, Lye, CC, Harrison, M, Sturgess, R, Galaska, R, Healey, C, Whiteman, J, Czaijkowski, M, Gray, C, Gunasekera, A, Gyawli, P, Premchand, P, Mann, S, Elliott, K, Kapur, K, Watson, A, Foster, G, Trembling, P, Subhani, J, Harvey, R, McCorry, R, Adgey, C, Hobson, L, Mulvaney-Jones, C, Evans, R, Mathialahan, T, Ramanaden, D, Gasem, J, Van, DG, Shorrock, C, Seward, K, Southern, P, Tibble, J, Penn, R, Gorard, D, Maiden, J, Damant, R, Palegwala, A, Jones, S, Alexander, GJ & M 2018, 'Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score', The Lancet Gastroenterology and Hepatology, vol. 3, no. 9, pp. 626-634. https://doi.org/10.1016/s2468-1253(18)30163-8

TY - JOUR

T1 - Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

AU - Carbone, Marco

AU - Nardi, Alessandra

AU - Flack, Steve

AU - Carpino, Guido

AU - Varvaropoulou, Nikoletta

AU - Gavrila, Caius

AU - Spicer, Ann

AU - Badrock, Jonathan

AU - Bernuzzi, Francesca

AU - Cardinale, Vincenzo

AU - Ainsworth, Holly F.

AU - Heneghan, Michael A.

AU - Thorburn, Douglas

AU - Bathgate, Andrew

AU - Jones, R

AU - Neuberger, James M.

AU - Battezzati, Pier Maria

AU - Zuin, Massimo

AU - Taylor-Robinson, Simon

AU - Donato, Maria F.

AU - Kirby, John

AU - Mitchell-Thain, Robert

AU - Floreani, Annarosa

AU - Sampaziotis, Fotios

AU - Muratori, Luigi

AU - Alvaro, Domenico

AU - Marzioni, Marco

AU - Miele, Luca

AU - Marra, Fabio

AU - Giannini, Edoardo

AU - Gaudio, Eugenio

AU - Ronca, Vincenzo

AU - Bonato, Giulia

AU - Cristoferi, Laura

AU - Malinverno, Federica

AU - Gerussi, Alessio

AU - Stocken, Deborah D.

AU - Cordell, Heather J.

AU - Hirschfield, Gideon M.

AU - Alexander, Graeme J.

AU - Sandford, Richard N.

AU - Jones, DE

AU - Invernizzi, Pietro

AU - Mells, George F.

AU - Thomas, Caradog

AU - Rahman, Meshbah

AU - Yapp, Tom

AU - Lye, Ch'ng C

AU - Harrison, Melanie

AU - Sturgess, R

AU - Galaska, R

AU - Healey, C

AU - Whiteman, J

AU - Czaijkowski, M

AU - Gray, C

AU - Gunasekera, A

AU - Gyawli, P

AU - Premchand, P

AU - Mann, S

AU - Elliott, K

AU - Kapur, K

AU - Watson, A

AU - Foster, G

AU - Trembling, P

AU - Subhani, J

AU - Harvey, R

AU - McCorry, R

AU - Adgey, C

AU - Hobson, L

AU - Mulvaney-Jones, C

AU - Evans, R

AU - Mathialahan, T

AU - Ramanaden, D

AU - Gasem, J

AU - Van, Duyvenvoorde G

AU - Shorrock, C

AU - Seward, K

AU - Southern, P

AU - Tibble, J

AU - Penn, R

AU - Gorard, D

AU - Maiden, J

AU - Damant, R

AU - Palegwala, A

AU - Jones, S

AU - Alexander, Graeme J.

AU - M, null

PY - 2018/9

Y1 - 2018/9

U2 - 10.1016/s2468-1253(18)30163-8

DO - 10.1016/s2468-1253(18)30163-8

M3 - Article

SN - 2468-1253

VL - 3

SP - 626

EP - 634

JO - The Lancet Gastroenterology and Hepatology

JF - The Lancet Gastroenterology and Hepatology

IS - 9

ER -