Abstract
Rapid elimination of remifentanil facilitates application of intense opioid effect during general anaesthesia whilst maintaining prompt emergence. Interruptions in remifentanil supply mean clinicians must relearn titration of pharmacokinetically longer-acting opioids to achieve appropriate levels of opioid effect whilst maintaining acceptable recovery times. Opioid-free anaesthesia is achievable for many minor and intermediate surgical procedures for which remifentanil might have been used previously.
| Original language | English |
|---|---|
| Pages (from-to) | 649-651 |
| Number of pages | 3 |
| Journal | British Journal of Anaesthesia |
| Volume | 129 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Nov 2022 |
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Keywords
- alfentanil
- pharmacodynamics
- pharmacokinetics
- propofol
- remifentanil
- supply chain