Potential responses to remifentanil supply shortages

J. Robert Sneyd

doi:10.1016/j.bja.2022.08.001

Potential responses to remifentanil supply shortages

J. Robert Sneyd

Faculty of Health

Research output: Contribution to journal › Editorial

Abstract

Rapid elimination of remifentanil facilitates application of intense opioid effect during general anaesthesia whilst maintaining prompt emergence. Interruptions in remifentanil supply mean clinicians must relearn titration of pharmacokinetically longer-acting opioids to achieve appropriate levels of opioid effect whilst maintaining acceptable recovery times. Opioid-free anaesthesia is achievable for many minor and intermediate surgical procedures for which remifentanil might have been used previously.

Original language	English
Pages (from-to)	649-651
Number of pages	3
Journal	British Journal of Anaesthesia
Volume	129
Issue number	5
DOIs	https://doi.org/10.1016/j.bja.2022.08.001
Publication status	Published - Nov 2022

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Keywords

alfentanil
pharmacodynamics
pharmacokinetics
propofol
remifentanil
supply chain

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10.1016/j.bja.2022.08.001

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abstract = "Rapid elimination of remifentanil facilitates application of intense opioid effect during general anaesthesia whilst maintaining prompt emergence. Interruptions in remifentanil supply mean clinicians must relearn titration of pharmacokinetically longer-acting opioids to achieve appropriate levels of opioid effect whilst maintaining acceptable recovery times. Opioid-free anaesthesia is achievable for many minor and intermediate surgical procedures for which remifentanil might have been used previously.",

keywords = "alfentanil, pharmacodynamics, pharmacokinetics, propofol, remifentanil, supply chain",

author = "Sneyd, {J. Robert}",

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AB - Rapid elimination of remifentanil facilitates application of intense opioid effect during general anaesthesia whilst maintaining prompt emergence. Interruptions in remifentanil supply mean clinicians must relearn titration of pharmacokinetically longer-acting opioids to achieve appropriate levels of opioid effect whilst maintaining acceptable recovery times. Opioid-free anaesthesia is achievable for many minor and intermediate surgical procedures for which remifentanil might have been used previously.

KW - alfentanil

KW - pharmacodynamics

KW - pharmacokinetics

KW - propofol

KW - remifentanil

KW - supply chain

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JF - British Journal of Anaesthesia

IS - 5

ER -

Potential responses to remifentanil supply shortages

Abstract

ASJC Scopus subject areas

Keywords

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