Pesticide residues and health risk assessment in tomatoes and lettuces from farms of metropolitan region Chile

Sebastian Elgueta*, Marcela Valenzuela, Marcela Fuentes, Pablo Meza, Juan Pablo Manzur, Shaofeng Liu, Guoqing Zhao, Arturo Correa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Over the last years, the detection of pesticide residues in the official food surveillance programs of Chile has been increased, mainly in fresh vegetables such as tomatoes and lettuces. The Metropolitana Region of Chile presents the highest detections in the country. The lack of evaluations of toxicological risks in human health have increased uncertainty of the potential effects of pesticides exposures in the Chilean population. This research aims to determinate health risks assessment of pesticide residues associated to tomatoes and lettuces produced in Metropolitana Region. The findings of this study reveal that tomatoes and lettuces cultivated in the MR show more than 50% of samples with one or multiple pesticides residues. From the total samples, 16% were over the Chilean Maximum Residue Levels (MRLs). The main pesticides detected in tomatoes and lettuces were methamidophos, methomyl, difenoconazole, cyprodinil and boscalid. The results obtained using the official data of the Ministry of Health of Chile (MINSAL) compared to the World Health Organization (WHO), describe relevant risks through the Estimated Daily Intakes (EDI), Hazard Quotients (HQ) and Hazard Index (HI) for the Chilean population due to high concentrations of methamidophos, methomyl and cyprodinil. More restrictions for the use of methamidophos, methomyl, difenoconazole, cyprodinil and boscalid and effective control programs should be implemented in order to mitigate the impacts on the Chilean population.

Original languageEnglish
Article number355
JournalMolecules
Volume25
Issue number2
DOIs
Publication statusPublished - 15 Jan 2020

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Keywords

  • Hazard Quotient HQ
  • Health risk assessment
  • Maximum Residue Levels (MRL)
  • Methamidophos
  • Methomyl
  • Metropolitana Region of Chile

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