Abstract
A method is provided for screening, risk assessment, prevention and early diagnosis ofperiodontal disease and/or peri-implantitis, patient-centred point-of-care periodontal therapy and monitoring treatment outcomes in a subject. The method comprises:collecting subgingival plaque samples from one or more sites around one or more teeth; extracting lipopolysaccharides (LPS, also known as lipoglycans or endotoxin) from the or each sample; and assaying sub-gingival LPS activity after extraction, using recombinant Factor C (EndoZyme or LAL assay).
Original language | English |
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Patent number | GB2549712 |
Publication status | Published - 1 Nov 2017 |
Keywords
- biomarkers
- lipopolysaccharide
- periodontitis