TY - JOUR
T1 - Intraocular lens opacification after corneal endothelial keratoplasty
T2 - Electron microscopy and x-ray element spectroscopy analysis
AU - Park, Jonathan C.
AU - Habib, Nabil E.
AU - Moate, Roy M.
N1 - Publisher Copyright:
© 2015 ASCRS and ESCRS.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Purpose To assess a newly recognized long-term complication of Descemet-stripping automated endothelial keratoplasty (DSAEK). Setting Plymouth Royal Eye Infirmary and Plymouth Electron Microscope Centre, Plymouth, United Kingdom. Design Retrospective case series. Methods This study evaluated cases of intraocular lens (IOL) opacification that developed after uneventful DSAEK. None of the IOLs was previously known to opacify. In 1 case, the opacified IOL was explanted and analyzed using detailed light microscopy, scanning electron microscopic (SEM) analysis, and element x-ray spectroscopy. Results In all 5 cases, the IOL was hydrophilic acrylic and the eye developed IOL anterior surface opacification 4 to 12 months after DSAEK. In 1 eye, the opacification was symptomatic; thus, an IOL exchange was performed. Light microscopy and SEM analysis of the explanted IOL confirmed opacification on the anterior surface and subsurface areas. X-ray element spectroscopy showed the granules were composed of calcium and phosphorous. Conclusions These cases indicate that IOL opacification after DSAEK is a late, although newly recognized, complication of endothelial keratoplasty. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.
AB - Purpose To assess a newly recognized long-term complication of Descemet-stripping automated endothelial keratoplasty (DSAEK). Setting Plymouth Royal Eye Infirmary and Plymouth Electron Microscope Centre, Plymouth, United Kingdom. Design Retrospective case series. Methods This study evaluated cases of intraocular lens (IOL) opacification that developed after uneventful DSAEK. None of the IOLs was previously known to opacify. In 1 case, the opacified IOL was explanted and analyzed using detailed light microscopy, scanning electron microscopic (SEM) analysis, and element x-ray spectroscopy. Results In all 5 cases, the IOL was hydrophilic acrylic and the eye developed IOL anterior surface opacification 4 to 12 months after DSAEK. In 1 eye, the opacification was symptomatic; thus, an IOL exchange was performed. Light microscopy and SEM analysis of the explanted IOL confirmed opacification on the anterior surface and subsurface areas. X-ray element spectroscopy showed the granules were composed of calcium and phosphorous. Conclusions These cases indicate that IOL opacification after DSAEK is a late, although newly recognized, complication of endothelial keratoplasty. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.
UR - http://www.scopus.com/inward/record.url?scp=84919430508&partnerID=8YFLogxK
U2 - 10.1016/j.jcrs.2014.05.035
DO - 10.1016/j.jcrs.2014.05.035
M3 - Article
C2 - 25532641
AN - SCOPUS:84919430508
SN - 0886-3350
VL - 41
SP - 140
EP - 145
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 1
ER -