Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Craig S. Anderson; Yining Huang; Richard I. Lindley; X Chen; Hisatomi Arima; G Chen; Qiang Li; Laurent Billot; Candice Delcourt; Philip M. Bath; Joseph P. Broderick; Andrew M. Demchuk; Geoffrey A. Donnan; AC Durham; Pablo M. Lavados; T-H Lee; Christopher Levi; SO Martins; Veronica V. Olavarria; JD Pandian; Mark W. Parsons; Octavio M. Pontes-Neto; Stefano Ricci; Shoichiro Sato; Vijay K. Sharma; Federico Silva; Lili Song; NH Thang; Joanna M. Wardlaw; J-G Wang; X Wang; Mark Woodward; John Chalmers; Thompson G. Robinson; Craig S. Anderson; Yining Huang; Richard I. Lindley; X Chen; Hisatomi Arima; G Chen; Qiang Li; Laurent Billot; Candice Delcourt; Philip M. Bath; Joseph P. Broderick; Andrew M. Demchuk; Geoffrey A. Donnan; AC Durham; Pablo M. Lavados; T-H Lee; Christopher Levi; SO Martins; Veronica V. Olavarria; JD Pandian; Mark W. Parsons; Octavio M. Pontes-Neto; Stefano Ricci; Shoichiro Sato; Vijay K. Sharma; Federico Silva; Lili Song; NH Thang; Joanna M. Wardlaw; J-G Wang; X Wang; Mark Woodward; John Chalmers; Thompson G. Robinson; Jong S. Kim; Christian Stapf; R. John Simes; Graeme J. Hankey; Peter Sandercock; Marie Germaine Bousser; K. S.Lawrence Wong; Anish Scaria; Yoichiro Hirakawa; Tom J. Moullaali; Cheryl Carcel; Penny Gordon; Sully X. Fuentes-Patarroyo; Dino Benito; R Chen; Y Cao; A Kunchok; S Winters; S Coutts; S Yoshimura; S You; J Yang; G Wu; S Zhang; L Manning; A Mistri; Haun

doi:10.1016/s0140-6736(19)30038-8

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Craig S. Anderson^*
, Yining Huang
, Richard I. Lindley
, X Chen
, Hisatomi Arima
, G Chen
, Qiang Li
, Laurent Billot
, Candice Delcourt
, Philip M. Bath
, Joseph P. Broderick
, Andrew M. Demchuk
, Geoffrey A. Donnan
, AC Durham
, Pablo M. Lavados
, T-H Lee
, Christopher Levi
, SO Martins
, Veronica V. Olavarria
, JD Pandian

Mark W. Parsons, Octavio M. Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Federico Silva, Lili Song, NH Thang, Joanna M. Wardlaw, J-G Wang, X Wang, Mark Woodward, John Chalmers, Thompson G. Robinson, Craig S. Anderson^*, Yining Huang, Richard I. Lindley, X Chen, Hisatomi Arima, G Chen, Qiang Li, Laurent Billot, Candice Delcourt, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, AC Durham, Pablo M. Lavados, T-H Lee, Christopher Levi, SO Martins, Veronica V. Olavarria, JD Pandian, Mark W. Parsons, Octavio M. Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Federico Silva, Lili Song, NH Thang, Joanna M. Wardlaw, J-G Wang, X Wang, Mark Woodward, John Chalmers, Thompson G. Robinson, Jong S. Kim, Christian Stapf, R. John Simes, Graeme J. Hankey, Peter Sandercock, Marie Germaine Bousser, K. S.Lawrence Wong, Anish Scaria, Yoichiro Hirakawa, Tom J. Moullaali, Cheryl Carcel, Penny Gordon, Sully X. Fuentes-Patarroyo, Dino Benito, R Chen, Y Cao, A Kunchok, S Winters, S Coutts, S Yoshimura, S You, J Yang, G Wu, S Zhang, L Manning, A Mistri, Haun

^*Corresponding author for this work

Peking University
Royal Prince Alfred Hospital
University of New South Wales
University of Sydney
Fukuoka University
University of Nottingham
University of Cincinnati
University of Calgary
University of Melbourne
Clínica Alemana de Santiago
Universidad de Chile
Christian Medical College
Hunter Medical Research Institute, Australia
Ingham Institute for Applied Medical Research
University of Newcastle
Chang Gung University
Universidade de São Paulo
UO Neurologia
National Cerebral and Cardiovascular Center
MOH Holdings Pte Ltd.
National University of Singapore
International Hospital of Colombia
University of Edinburgh
Johns Hopkins University
University of Oxford
Glenfield Hospital
University of Leicester

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	877-888
Number of pages	0
Journal	The Lancet
Volume	393
Issue number	10174
DOIs	https://doi.org/10.1016/s0140-6736(19)30038-8
Publication status	Published - Mar 2019
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/s0140-6736(19)30038-8

Cite this

Anderson, C. S., Huang, Y., Lindley, R. I., Chen, X., Arima, H., Chen, G., Li, Q., Billot, L., Delcourt, C., Bath, P. M., Broderick, J. P., Demchuk, A. M., Donnan, G. A., Durham, AC., Lavados, P. M., Lee, T.-H., Levi, C., Martins, SO., Olavarria, V. V., ... Haun (2019). Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial. The Lancet, 393(10174), 877-888. https://doi.org/10.1016/s0140-6736(19)30038-8

@article{13ac8a831bd94f688e16a3cda4348150,

title = "Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial",

author = "Anderson, \{Craig S.\} and Yining Huang and Lindley, \{Richard I.\} and X Chen and Hisatomi Arima and G Chen and Qiang Li and Laurent Billot and Candice Delcourt and Bath, \{Philip M.\} and Broderick, \{Joseph P.\} and Demchuk, \{Andrew M.\} and Donnan, \{Geoffrey A.\} and AC Durham and Lavados, \{Pablo M.\} and T-H Lee and Christopher Levi and SO Martins and Olavarria, \{Veronica V.\} and JD Pandian and Parsons, \{Mark W.\} and Pontes-Neto, \{Octavio M.\} and Stefano Ricci and Shoichiro Sato and Sharma, \{Vijay K.\} and Federico Silva and Lili Song and NH Thang and Wardlaw, \{Joanna M.\} and J-G Wang and X Wang and Mark Woodward and John Chalmers and Robinson, \{Thompson G.\} and Anderson, \{Craig S.\} and Yining Huang and Lindley, \{Richard I.\} and X Chen and Hisatomi Arima and G Chen and Qiang Li and Laurent Billot and Candice Delcourt and Bath, \{Philip M.\} and Broderick, \{Joseph P.\} and Demchuk, \{Andrew M.\} and Donnan, \{Geoffrey A.\} and AC Durham and Lavados, \{Pablo M.\} and T-H Lee and Christopher Levi and SO Martins and Olavarria, \{Veronica V.\} and JD Pandian and Parsons, \{Mark W.\} and Pontes-Neto, \{Octavio M.\} and Stefano Ricci and Shoichiro Sato and Sharma, \{Vijay K.\} and Federico Silva and Lili Song and NH Thang and Wardlaw, \{Joanna M.\} and J-G Wang and X Wang and Mark Woodward and John Chalmers and Robinson, \{Thompson G.\} and Kim, \{Jong S.\} and Christian Stapf and Simes, \{R. John\} and Hankey, \{Graeme J.\} and Peter Sandercock and Bousser, \{Marie Germaine\} and Wong, \{K. S.Lawrence\} and Anish Scaria and Yoichiro Hirakawa and Moullaali, \{Tom J.\} and Cheryl Carcel and Penny Gordon and Fuentes-Patarroyo, \{Sully X.\} and Dino Benito and R Chen and Y Cao and A Kunchok and S Winters and S Coutts and S Yoshimura and S You and J Yang and G Wu and S Zhang and L Manning and A Mistri and Haun",

year = "2019",

month = mar,

doi = "10.1016/s0140-6736(19)30038-8",

language = "English",

volume = "393",

pages = "877--888",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier B.V.",

number = "10174",

}

Anderson, CS, Huang, Y, Lindley, RI, Chen, X, Arima, H, Chen, G, Li, Q, Billot, L, Delcourt, C, Bath, PM, Broderick, JP, Demchuk, AM, Donnan, GA, Durham, AC, Lavados, PM, Lee, T-H, Levi, C, Martins, SO, Olavarria, VV, Pandian, JD, Parsons, MW, Pontes-Neto, OM, Ricci, S, Sato, S, Sharma, VK, Silva, F, Song, L, Thang, NH, Wardlaw, JM, Wang, J-G, Wang, X, Woodward, M, Chalmers, J, Robinson, TG, Anderson, CS, Huang, Y, Lindley, RI, Chen, X, Arima, H, Chen, G, Li, Q, Billot, L, Delcourt, C, Bath, PM, Broderick, JP, Demchuk, AM, Donnan, GA, Durham, AC, Lavados, PM, Lee, T-H, Levi, C, Martins, SO, Olavarria, VV, Pandian, JD, Parsons, MW, Pontes-Neto, OM, Ricci, S, Sato, S, Sharma, VK, Silva, F, Song, L, Thang, NH, Wardlaw, JM, Wang, J-G, Wang, X, Woodward, M, Chalmers, J, Robinson, TG, Kim, JS, Stapf, C, Simes, RJ, Hankey, GJ, Sandercock, P, Bousser, MG, Wong, KSL, Scaria, A, Hirakawa, Y, Moullaali, TJ, Carcel, C, Gordon, P, Fuentes-Patarroyo, SX, Benito, D, Chen, R, Cao, Y, Kunchok, A, Winters, S, Coutts, S, Yoshimura, S, You, S, Yang, J, Wu, G, Zhang, S, Manning, L, Mistri, A & Haun 2019, 'Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial', The Lancet, vol. 393, no. 10174, pp. 877-888. https://doi.org/10.1016/s0140-6736(19)30038-8

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial. / Anderson, Craig S.; Huang, Yining; Lindley, Richard I. et al.
In: The Lancet, Vol. 393, No. 10174, 03.2019, p. 877-888.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

AU - Anderson, Craig S.

AU - Huang, Yining

AU - Lindley, Richard I.

AU - Chen, X

AU - Arima, Hisatomi

AU - Chen, G

AU - Li, Qiang

AU - Billot, Laurent

AU - Delcourt, Candice

AU - Bath, Philip M.

AU - Broderick, Joseph P.

AU - Demchuk, Andrew M.

AU - Donnan, Geoffrey A.

AU - Durham, AC

AU - Lavados, Pablo M.

AU - Lee, T-H

AU - Levi, Christopher

AU - Martins, SO

AU - Olavarria, Veronica V.

AU - Pandian, JD

AU - Parsons, Mark W.

AU - Pontes-Neto, Octavio M.

AU - Ricci, Stefano

AU - Sato, Shoichiro

AU - Sharma, Vijay K.

AU - Silva, Federico

AU - Song, Lili

AU - Thang, NH

AU - Wardlaw, Joanna M.

AU - Wang, J-G

AU - Wang, X

AU - Woodward, Mark

AU - Chalmers, John

AU - Robinson, Thompson G.

AU - Anderson, Craig S.

AU - Huang, Yining

AU - Lindley, Richard I.

AU - Chen, X

AU - Arima, Hisatomi

AU - Chen, G

AU - Li, Qiang

AU - Billot, Laurent

AU - Delcourt, Candice

AU - Bath, Philip M.

AU - Broderick, Joseph P.

AU - Demchuk, Andrew M.

AU - Donnan, Geoffrey A.

AU - Durham, AC

AU - Lavados, Pablo M.

AU - Lee, T-H

AU - Levi, Christopher

AU - Martins, SO

AU - Olavarria, Veronica V.

AU - Pandian, JD

AU - Parsons, Mark W.

AU - Pontes-Neto, Octavio M.

AU - Ricci, Stefano

AU - Sato, Shoichiro

AU - Sharma, Vijay K.

AU - Silva, Federico

AU - Song, Lili

AU - Thang, NH

AU - Wardlaw, Joanna M.

AU - Wang, J-G

AU - Wang, X

AU - Woodward, Mark

AU - Chalmers, John

AU - Robinson, Thompson G.

AU - Kim, Jong S.

AU - Stapf, Christian

AU - Simes, R. John

AU - Hankey, Graeme J.

AU - Sandercock, Peter

AU - Bousser, Marie Germaine

AU - Wong, K. S.Lawrence

AU - Scaria, Anish

AU - Hirakawa, Yoichiro

AU - Moullaali, Tom J.

AU - Carcel, Cheryl

AU - Gordon, Penny

AU - Fuentes-Patarroyo, Sully X.

AU - Benito, Dino

AU - Chen, R

AU - Cao, Y

AU - Kunchok, A

AU - Winters, S

AU - Coutts, S

AU - Yoshimura, S

AU - You, S

AU - Yang, J

AU - Wu, G

AU - Zhang, S

AU - Manning, L

AU - Mistri, A

AU - Haun, null

PY - 2019/3

Y1 - 2019/3

U2 - 10.1016/s0140-6736(19)30038-8

DO - 10.1016/s0140-6736(19)30038-8

M3 - Article

SN - 0140-6736

VL - 393

SP - 877

EP - 888

JO - The Lancet

JF - The Lancet

IS - 10174

ER -