Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study

Mie Rizig; Sara Bandres-Ciga; Mary B. Makarious; Oluwadamilola Omolara Ojo; Peter Wild Crea; Oladunni Victoria Abiodun; Kristin S. Levine; Sani Atta Abubakar; Charles Obiora Achoru; Dan Vitale; Olaleye Akinmola Adeniji; Osigwe Paul Agabi; Mathew J. Koretsky; Uchechi Agulanna; Deborah A. Hall; Rufus Olusola Akinyemi; Tao Xie; Mohammed Wulgo Ali; Ejaz A. Shamim; Ifeyinwa Ani-Osheku; Mahesh Padmanaban; Ohwotemu Michael Arigbodi; David G. Standaert; Abiodun Hamzat Bello; Marissa N. Dean; Cyril Oshomah Erameh; Inas Elsayed; Temitope Hannah Farombi; Olaitan Okunoye; Michael Bimbola Fawale; Kimberley J. Billingsley; Frank Aiwansoba Imarhiagbe; Pilar Alvarez Jerez; Emmanuel Uzodinma Iwuozo; Breeana Baker; Morenikeji Adeyoyin Komolafe; Laksh Malik; Paul Osemeke Nwani; Kensuke Daida; Ernest Okwundu Nwazor; Abigail Miano-Burkhardt; Yakub Wilberforce Nyandaiti; Zih Hua Fang; Yahaya Olugbo Obiabo; Jillian H. Kluss; Olanike Adedoyin Odeniyi; Dena G. Hernandez; Francis Ehidiamen Odiase; Nahid Tayebi; FI Ojini; E Sidranksy; GA Onwuegbuzie; AM D'Souza; GO Osaigbovo; B Berhe; N Osemwegie; X Reed; OO Oshinaike; HL Leonard; FM Otubogun; CX Alvarado; SI Oyakhire; SI Ozomma; SC Samuel; FT Taiwo; KW Wahab; YA Zubair; H Iwaki; JJ Kim; HR Morris; J Hardy; MA Nalls; K Heilbron; L Norcliffe-Kaufmann; C Blauwendraat; H Houlden; A Singleton; NU Okubadejo; N Okubadejo; Oluwadamilola Omolara Ojo; Oladunni Victoria Abiodun; Charles Obiora Achoru; Osigwe Paul Agabi; Uchechi Agulanna; Rufus Olusola Akinyemi; Mohammed Wulgo Ali; Ani-Oshek

doi:10.1016/s1474-4422(23)00283-1

Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study

Mie Rizig
, Sara Bandres-Ciga
, Mary B. Makarious
, Oluwadamilola Omolara Ojo
, Peter Wild Crea
, Oladunni Victoria Abiodun
, Kristin S. Levine
, Sani Atta Abubakar
, Charles Obiora Achoru
, Dan Vitale
, Olaleye Akinmola Adeniji
, Osigwe Paul Agabi
, Mathew J. Koretsky
, Uchechi Agulanna
, Deborah A. Hall
, Rufus Olusola Akinyemi
, Tao Xie
, Mohammed Wulgo Ali
, Ejaz A. Shamim
, Ifeyinwa Ani-Osheku

Mahesh Padmanaban, Ohwotemu Michael Arigbodi, David G. Standaert, Abiodun Hamzat Bello, Marissa N. Dean, Cyril Oshomah Erameh, Inas Elsayed, Temitope Hannah Farombi, Olaitan Okunoye, Michael Bimbola Fawale, Kimberley J. Billingsley, Frank Aiwansoba Imarhiagbe, Pilar Alvarez Jerez, Emmanuel Uzodinma Iwuozo, Breeana Baker, Morenikeji Adeyoyin Komolafe, Laksh Malik, Paul Osemeke Nwani, Kensuke Daida, Ernest Okwundu Nwazor, Abigail Miano-Burkhardt, Yakub Wilberforce Nyandaiti, Zih Hua Fang, Yahaya Olugbo Obiabo, Jillian H. Kluss, Olanike Adedoyin Odeniyi, Dena G. Hernandez, Francis Ehidiamen Odiase, Nahid Tayebi, FI Ojini, E Sidranksy, GA Onwuegbuzie, AM D'Souza, GO Osaigbovo, B Berhe, N Osemwegie, X Reed, OO Oshinaike, HL Leonard, FM Otubogun, CX Alvarado, SI Oyakhire, SI Ozomma, SC Samuel, FT Taiwo, KW Wahab, YA Zubair, H Iwaki, JJ Kim, HR Morris, J Hardy, MA Nalls, K Heilbron, L Norcliffe-Kaufmann, C Blauwendraat, H Houlden, A Singleton, NU Okubadejo, N Okubadejo, Oluwadamilola Omolara Ojo, Oladunni Victoria Abiodun, Charles Obiora Achoru, Osigwe Paul Agabi, Uchechi Agulanna, Rufus Olusola Akinyemi, Mohammed Wulgo Ali, Ani-Oshek

University College London
National Institutes of Health
University of Lagos
General Hospital
Data Tecnica International
Ahmadu Bello University
University of Jos
Federal Medical Centre
Lagos University Teaching Hospital
Rush University
University of Ibadan
The University of Chicago
Federal Teaching Hospital Gombe
Kaiser Permanente
MidAtlantic Permanente Research Institute
Asokoro District Hospital, Abuja
Delta State University Nigeria
University of Alabama at Birmingham
University of Ilorin
Irrua Specialist Teaching Hospital
University of Gezira
Obafemi Awolowo University
University of Benin
Benue State University
Nnamdi Azikiwe University, Awka
Rivers State University Teaching Hospital
University of Maiduguri
German Center for Neurodegenerative Diseases
Federal University of Health Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1015-1025
Number of pages	0
Journal	The Lancet Neurology
Volume	22
Issue number	11
DOIs	https://doi.org/10.1016/s1474-4422(23)00283-1
Publication status	Published - Nov 2023
Externally published	Yes

Access to Document

10.1016/s1474-4422(23)00283-1

Cite this

Rizig, M., Bandres-Ciga, S., Makarious, M. B., Ojo, O. O., Crea, P. W., Abiodun, O. V., Levine, K. S., Abubakar, S. A., Achoru, C. O., Vitale, D., Adeniji, O. A., Agabi, O. P., Koretsky, M. J., Agulanna, U., Hall, D. A., Akinyemi, R. O., Xie, T., Ali, M. W., Shamim, E. A., ... Ani-Oshek (2023). Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study. The Lancet Neurology, 22(11), 1015-1025. https://doi.org/10.1016/s1474-4422(23)00283-1

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title = "Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study",

author = "Mie Rizig and Sara Bandres-Ciga and Makarious, \{Mary B.\} and Ojo, \{Oluwadamilola Omolara\} and Crea, \{Peter Wild\} and Abiodun, \{Oladunni Victoria\} and Levine, \{Kristin S.\} and Abubakar, \{Sani Atta\} and Achoru, \{Charles Obiora\} and Dan Vitale and Adeniji, \{Olaleye Akinmola\} and Agabi, \{Osigwe Paul\} and Koretsky, \{Mathew J.\} and Uchechi Agulanna and Hall, \{Deborah A.\} and Akinyemi, \{Rufus Olusola\} and Tao Xie and Ali, \{Mohammed Wulgo\} and Shamim, \{Ejaz A.\} and Ifeyinwa Ani-Osheku and Mahesh Padmanaban and Arigbodi, \{Ohwotemu Michael\} and Standaert, \{David G.\} and Bello, \{Abiodun Hamzat\} and Dean, \{Marissa N.\} and Erameh, \{Cyril Oshomah\} and Inas Elsayed and Farombi, \{Temitope Hannah\} and Olaitan Okunoye and Fawale, \{Michael Bimbola\} and Billingsley, \{Kimberley J.\} and Imarhiagbe, \{Frank Aiwansoba\} and Jerez, \{Pilar Alvarez\} and Iwuozo, \{Emmanuel Uzodinma\} and Breeana Baker and Komolafe, \{Morenikeji Adeyoyin\} and Laksh Malik and Nwani, \{Paul Osemeke\} and Kensuke Daida and Nwazor, \{Ernest Okwundu\} and Abigail Miano-Burkhardt and Nyandaiti, \{Yakub Wilberforce\} and Fang, \{Zih Hua\} and Obiabo, \{Yahaya Olugbo\} and Kluss, \{Jillian H.\} and Odeniyi, \{Olanike Adedoyin\} and Hernandez, \{Dena G.\} and Odiase, \{Francis Ehidiamen\} and Nahid Tayebi and FI Ojini and E Sidranksy and GA Onwuegbuzie and AM D'Souza and GO Osaigbovo and B Berhe and N Osemwegie and X Reed and OO Oshinaike and HL Leonard and FM Otubogun and CX Alvarado and SI Oyakhire and SI Ozomma and SC Samuel and FT Taiwo and KW Wahab and YA Zubair and H Iwaki and JJ Kim and HR Morris and J Hardy and MA Nalls and K Heilbron and L Norcliffe-Kaufmann and C Blauwendraat and H Houlden and A Singleton and NU Okubadejo and N Okubadejo and Ojo, \{Oluwadamilola Omolara\} and Abiodun, \{Oladunni Victoria\} and Achoru, \{Charles Obiora\} and Agabi, \{Osigwe Paul\} and Uchechi Agulanna and Akinyemi, \{Rufus Olusola\} and Ali, \{Mohammed Wulgo\} and Ani-Oshek",

year = "2023",

month = nov,

doi = "10.1016/s1474-4422(23)00283-1",

language = "English",

volume = "22",

pages = "1015--1025",

journal = "The Lancet Neurology",

issn = "1474-4422",

publisher = "Elsevier Ltd.",

number = "11",

}

Rizig, M, Bandres-Ciga, S, Makarious, MB, Ojo, OO, Crea, PW, Abiodun, OV, Levine, KS, Abubakar, SA, Achoru, CO, Vitale, D, Adeniji, OA, Agabi, OP, Koretsky, MJ, Agulanna, U, Hall, DA, Akinyemi, RO, Xie, T, Ali, MW, Shamim, EA, Ani-Osheku, I, Padmanaban, M, Arigbodi, OM, Standaert, DG, Bello, AH, Dean, MN, Erameh, CO, Elsayed, I, Farombi, TH, Okunoye, O, Fawale, MB, Billingsley, KJ, Imarhiagbe, FA, Jerez, PA, Iwuozo, EU, Baker, B, Komolafe, MA, Malik, L, Nwani, PO, Daida, K, Nwazor, EO, Miano-Burkhardt, A, Nyandaiti, YW, Fang, ZH, Obiabo, YO, Kluss, JH, Odeniyi, OA, Hernandez, DG, Odiase, FE, Tayebi, N, Ojini, FI, Sidranksy, E, Onwuegbuzie, GA, D'Souza, AM, Osaigbovo, GO, Berhe, B, Osemwegie, N, Reed, X, Oshinaike, OO, Leonard, HL, Otubogun, FM, Alvarado, CX, Oyakhire, SI, Ozomma, SI, Samuel, SC, Taiwo, FT, Wahab, KW, Zubair, YA, Iwaki, H, Kim, JJ, Morris, HR, Hardy, J, Nalls, MA, Heilbron, K, Norcliffe-Kaufmann, L, Blauwendraat, C, Houlden, H, Singleton, A, Okubadejo, NU, Okubadejo, N, Ojo, OO, Abiodun, OV, Achoru, CO, Agabi, OP, Agulanna, U, Akinyemi, RO, Ali, MW & Ani-Oshek 2023, 'Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study', The Lancet Neurology, vol. 22, no. 11, pp. 1015-1025. https://doi.org/10.1016/s1474-4422(23)00283-1

TY - JOUR

T1 - Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study

AU - Rizig, Mie

AU - Bandres-Ciga, Sara

AU - Makarious, Mary B.

AU - Ojo, Oluwadamilola Omolara

AU - Crea, Peter Wild

AU - Abiodun, Oladunni Victoria

AU - Levine, Kristin S.

AU - Abubakar, Sani Atta

AU - Achoru, Charles Obiora

AU - Vitale, Dan

AU - Adeniji, Olaleye Akinmola

AU - Agabi, Osigwe Paul

AU - Koretsky, Mathew J.

AU - Agulanna, Uchechi

AU - Hall, Deborah A.

AU - Akinyemi, Rufus Olusola

AU - Xie, Tao

AU - Ali, Mohammed Wulgo

AU - Shamim, Ejaz A.

AU - Ani-Osheku, Ifeyinwa

AU - Padmanaban, Mahesh

AU - Arigbodi, Ohwotemu Michael

AU - Standaert, David G.

AU - Bello, Abiodun Hamzat

AU - Dean, Marissa N.

AU - Erameh, Cyril Oshomah

AU - Elsayed, Inas

AU - Farombi, Temitope Hannah

AU - Okunoye, Olaitan

AU - Fawale, Michael Bimbola

AU - Billingsley, Kimberley J.

AU - Imarhiagbe, Frank Aiwansoba

AU - Jerez, Pilar Alvarez

AU - Iwuozo, Emmanuel Uzodinma

AU - Baker, Breeana

AU - Komolafe, Morenikeji Adeyoyin

AU - Malik, Laksh

AU - Nwani, Paul Osemeke

AU - Daida, Kensuke

AU - Nwazor, Ernest Okwundu

AU - Miano-Burkhardt, Abigail

AU - Nyandaiti, Yakub Wilberforce

AU - Fang, Zih Hua

AU - Obiabo, Yahaya Olugbo

AU - Kluss, Jillian H.

AU - Odeniyi, Olanike Adedoyin

AU - Hernandez, Dena G.

AU - Odiase, Francis Ehidiamen

AU - Tayebi, Nahid

AU - Ojini, FI

AU - Sidranksy, E

AU - Onwuegbuzie, GA

AU - D'Souza, AM

AU - Osaigbovo, GO

AU - Berhe, B

AU - Osemwegie, N

AU - Reed, X

AU - Oshinaike, OO

AU - Leonard, HL

AU - Otubogun, FM

AU - Alvarado, CX

AU - Oyakhire, SI

AU - Ozomma, SI

AU - Samuel, SC

AU - Taiwo, FT

AU - Wahab, KW

AU - Zubair, YA

AU - Iwaki, H

AU - Kim, JJ

AU - Morris, HR

AU - Hardy, J

AU - Nalls, MA

AU - Heilbron, K

AU - Norcliffe-Kaufmann, L

AU - Blauwendraat, C

AU - Houlden, H

AU - Singleton, A

AU - Okubadejo, NU

AU - Okubadejo, N

AU - Ojo, Oluwadamilola Omolara

AU - Abiodun, Oladunni Victoria

AU - Achoru, Charles Obiora

AU - Agabi, Osigwe Paul

AU - Agulanna, Uchechi

AU - Akinyemi, Rufus Olusola

AU - Ali, Mohammed Wulgo

AU - Ani-Oshek, null

PY - 2023/11

Y1 - 2023/11

U2 - 10.1016/s1474-4422(23)00283-1

DO - 10.1016/s1474-4422(23)00283-1

M3 - Article

SN - 1474-4422

VL - 22

SP - 1015

EP - 1025

JO - The Lancet Neurology

JF - The Lancet Neurology

IS - 11

ER -