Home-based versus centre-based cardiac rehabilitation: abridged Cochrane systematic review and meta-analysis

SA Buckingham, RS Taylor, K Jolly, A Zawada, SG Dean, A Cowie, RJ Norton, HM Dalal

Research output: Contribution to journalArticlepeer-review

Abstract

<jats:sec><jats:title>Objective</jats:title><jats:p>To update the Cochrane review comparing the effects of home-based and supervised centre-based cardiac rehabilitation (CR) on mortality and morbidity, quality of life, and modifiable cardiac risk factors in patients with heart disease.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Systematic review and meta-analysis. The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PsycINFO and CINAHL were searched up to October 2014, without language restriction. Randomised trials comparing home-based and centre-based CR programmes in adults with myocardial infarction, angina, heart failure or who had undergone coronary revascularisation were included.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>17 studies with 2172 patients were included. No difference was seen between home-based and centre-based CR in terms of: mortality (relative risk (RR) 0.79, 95% CI 0.43 to 1.47); cardiac events; exercise capacity (mean difference (MD) −0.10, −0.29 to 0.08); total cholesterol (MD 0.07 mmol/L, −0.24 to 0.11); low-density lipoprotein cholesterol (MD −0.06 mmol/L, −0.27 to 0.15); triglycerides (MD −0.16 mmol/L, −0.38 to 0.07); systolic blood pressure (MD 0.2 mm Hg, −3.4 to 3.8); smoking (RR 0.98, 0.79 to 1.21); health-related quality of life and healthcare costs. Lower high-density lipoprotein cholesterol (MD −0.07 mmol/L, −0.11 to −0.03, p=0.001) and lower diastolic blood pressure (MD −1.9 mm Hg, −0.8 to −3.0, p=0.009) were observed in centre-based participants. Home-based CR was associated with slightly higher adherence (RR 1.04, 95% CI 1.01 to 1.07).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Home-based and centre-based CR provide similar benefits in terms of clinical and health-related quality of life outcomes at equivalent cost for those with heart failure and following myocardial infarction and revascularisation.</jats:p></jats:sec>
Original languageEnglish
Pages (from-to)e000463-e000463
Number of pages0
JournalOpen Heart
Volume3
Issue number2
Early online date14 Sept 2016
DOIs
Publication statusPublished - Sept 2016

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