Get remimazolam off the bench and into the game

In a high-level sporting fixture, the introduction of a skilled player from the reserve bench can be a game changer. The introduction of propofol into clinical anaesthesia practice was a pharmacological game changer [1]. The drug rapidly assumed dominance over other intravenous options for induction of anaesthesia in children. Propofol use for maintenance does not yet rival that of the inhalational agent, sevoflurane, but acceptance is increasing [2] even in areas such as neonatal anaesthesia and intensive care sedation. None of the other hypnotic drugs available or investigated have competed with propofol in adults or children [3], although remimazolam is a recent competitor.