@article{9b3f045b118b4a2c83652c287d2931d5,
title = "Fibroblast Growth Factor Receptor-2 Polymorphism rs2981582 is Correlated With Progression-free Survival and Overall Survival in Patients With Metastatic Clear-cell Renal Cell Carcinoma Treated With Sunitinib",
abstract = "We describe a potential biomarker associated with progression-free survival and overall survival on sunitinib in metastatic clear-cell renal cell carcinoma. rs2981582 is a polymorphism in the fibroblast growth factor receptor 2. In our series of 154 patients treated with sunitinib, the TT-variant, present in 13% of the patients, was associated with shorter progression-free survival and overall survival.",
keywords = "Angiogenesis inhibitor, Biomarker, Outcome, Prognosis, Single nucleotide polymorphisms",
author = "Maxime Vanmechelen and Diether Lambrechts and {Van Brussel}, Thomas and Annelies Verbiest and Gabrielle Couchy and Patrick Sch{\"o}ffski and Herlinde Dumez and Debruyne, {Philip R.} and Evelyne Lerut and Machiels, {Jean Pascal} and Vincent Richard and Maarten Albersen and Vincent Verschaeve and St{\'e}phane Oudard and Arnaud M{\'e}jean and Pascal Wolter and Jessica Zucman-Rossi and Benoit Beuselinck",
note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2019",
month = apr,
doi = "10.1016/j.clgc.2018.11.002",
language = "English",
volume = "17",
pages = "e235--e246",
journal = "Clinical Genitourinary Cancer",
issn = "1558-7673",
publisher = "Elsevier Inc.",
number = "2",
}