Abstract
<jats:p> The dynamic response of critical closing pressure (CrCP) and resistance-area product (RAP) of the cerebral circulation to a step change in mean arterial pressure can shed light on the nonstationary changes induced by paced hyperventilation and the effects of hypocapnia on the autoregulation of cerebral blood flow. Contrary to hypercapnia, where the response is dominated by CrCP, hypocapnia shows an initial depression of cerebral autoregulation, followed by improvements controlled by changes in RAP. </jats:p>
Original language | English |
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Pages (from-to) | 311-319 |
Number of pages | 0 |
Journal | Journal of Applied Physiology |
Volume | 133 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1 Aug 2022 |