TY - JOUR
T1 - Diffuse large B-cell lymphoma associated with papillary thyroid carcinoma
T2 - a case report and systematic review on management and outcomes
AU - Lincango, Eddy P.
AU - Serrano, Luis F.
AU - Vallejo, Sebastian
AU - Solis-Pazmino, Paola
AU - Garcia-Bautista, Andrea
AU - Acosta, William
AU - Ponce, Oscar J.
AU - Salazar-Vega, Jorge
AU - Garcia, Cristhian
N1 - Publisher Copyright:
© 2024 Published by Oxford University Press and JSCR Publishing Ltd.
PY - 2024/5/1
Y1 - 2024/5/1
N2 - Primary thyroid lymphoma is a rare thyroid cancer, comprising < 5% of thyroid neoplasms. Most cases are diffuse large B-cell lymphoma (DLBCL). Coexistence with papillary thyroid cancer (PTC) is extremely rare. This study presents a case of a 55-year-old woman with DLBCL and micropapillary thyroid cancer who underwent lobectomy, chemotherapy, and radiotherapy. Additionally, we performed a systematic review of 10 cases, including the reported case. The risk of bias in case reports varied. DLBCL diagnoses were mainly made after surgery, with total thyroidectomy being the most common surgical procedure. Chemotherapy was administered in most cases, and radiotherapy was used in some cases. Long-term outcomes indicated a low recurrence rate. While some debate the role of surgery in thyroid lymphoma, this study suggests that surgery should be considered in selected cases. Further research is needed to determine optimal treatment strategies for DLBCL with PTC.
AB - Primary thyroid lymphoma is a rare thyroid cancer, comprising < 5% of thyroid neoplasms. Most cases are diffuse large B-cell lymphoma (DLBCL). Coexistence with papillary thyroid cancer (PTC) is extremely rare. This study presents a case of a 55-year-old woman with DLBCL and micropapillary thyroid cancer who underwent lobectomy, chemotherapy, and radiotherapy. Additionally, we performed a systematic review of 10 cases, including the reported case. The risk of bias in case reports varied. DLBCL diagnoses were mainly made after surgery, with total thyroidectomy being the most common surgical procedure. Chemotherapy was administered in most cases, and radiotherapy was used in some cases. Long-term outcomes indicated a low recurrence rate. While some debate the role of surgery in thyroid lymphoma, this study suggests that surgery should be considered in selected cases. Further research is needed to determine optimal treatment strategies for DLBCL with PTC.
UR - https://www.scopus.com/pages/publications/85194276080
U2 - 10.1093/jscr/rjad658
DO - 10.1093/jscr/rjad658
M3 - Article
AN - SCOPUS:85194276080
SN - 2042-8812
VL - 2024
JO - Journal of Surgical Case Reports
JF - Journal of Surgical Case Reports
IS - 5
M1 - rjad658
ER -
