Determination of minimal inhibitory concentration of cadmium for Brevibacillus agri C15 and Brevibacillus agri C15 Cdr

Nadia Jebril*, Rich Boden, Charlotte Braungardt

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceedings published in a bookpeer-review

Abstract

Determining resistance by minimal inhibitory concentration (MIC) assay is important in handling bacteria. Here we describe a protocol for identifying the MIC for cadmium (Cd) of Brevibacillus agri C15 and Brevibacillus agri C15 CdR to assist researchers incorrectly confirming the resistance of isolates. In addition, the effects of Cd on the cell-surface structure and morphology, endospore formation, poly-β-hydroxybutyrate and polyphosphate granules were investigated. Its MIC to Cd were 16 ± 0.7 mM and 21± 0.4 mM Cd, respectively. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed no morphological effects of Cd on either of the strains. Both strains have terminal endospores, poly-β-hydroxybutyrate granules and an absence of polyphosphate granules. This projected assay to determine the MIC of cadmium can be applied to the study of new agents with B. agri C15 and B. agri C15 CdR and in laboratory routines for other bacteria.

Original languageEnglish
Title of host publicationInternational Conference on Scientific Research and Innovation 2022, ICSRI 2022
EditorsJustin Link, Haider Raad, Sarah McGrath, Adawiya Haider, T.A. Mohammed Muayad, Hanady AL-Shmgani, Thaer Al-Jadir
PublisherAmerican Institute of Physics Inc.
Volume2820
ISBN (Electronic)9780735445598
DOIs
Publication statusPublished - 26 Jun 2023
EventInternational Conference on Scientific Research and Innovation 2022, ICSRI 2022 - Hybrid, Cincinnati, United States
Duration: 10 Apr 202211 Apr 2022

Publication series

NameAIP Conference Proceedings
Volume2820
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

ConferenceInternational Conference on Scientific Research and Innovation 2022, ICSRI 2022
Country/TerritoryUnited States
CityHybrid, Cincinnati
Period10/04/2211/04/22

ASJC Scopus subject areas

  • General Physics and Astronomy

Keywords

  • Brevibacillus
  • cadmium
  • endospore
  • minimum inhibitory concentration
  • poly-β-hydroxybutyrate granule
  • polyphosphate granule
  • SEM
  • TEM

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