Cushing's disease treated by trans-sphenoidal selective adenomectomy in mid-pregnancy

A. Mellor; R. D. Harvey; L. H. Pobereskin; J. R. Sneyd

doi:10.1093/bja/80.6.850

Cushing's disease treated by trans-sphenoidal selective adenomectomy in mid-pregnancy

A. Mellor, R. D. Harvey, L. H. Pobereskin, J. R. Sneyd^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The clinical course and diagnosis of a patient with Cushing's disease complicated by pregnancy is described, and the anaesthetic management of trans-sphenoidal selective adenomectomy performed during the second trimester outlined. Problems included obesity, diabetes, hypertension and a suboptimal airway. Fibreoptic awake intubation and intravenous anaesthesia were used. Insulin requirements decreased substantially after surgery. Early administration of hydrocortisone after surgery avoided the risk of an addisonian crisis but delayed biochemical confirmation of a metabolic cure.

Original language	English
Pages (from-to)	850-852
Number of pages	3
Journal	British Journal of Anaesthesia
Volume	80
Issue number	6
DOIs	https://doi.org/10.1093/bja/80.6.850
Publication status	Published - 1998
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Keywords

Anaesthesia general
Cushing's syndrome
Hypophysectomy
Pituitary neoplasms
Pregnancy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/bja/80.6.850

Cite this

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abstract = "The clinical course and diagnosis of a patient with Cushing's disease complicated by pregnancy is described, and the anaesthetic management of trans-sphenoidal selective adenomectomy performed during the second trimester outlined. Problems included obesity, diabetes, hypertension and a suboptimal airway. Fibreoptic awake intubation and intravenous anaesthesia were used. Insulin requirements decreased substantially after surgery. Early administration of hydrocortisone after surgery avoided the risk of an addisonian crisis but delayed biochemical confirmation of a metabolic cure.",

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AU - Sneyd, J. R.

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AB - The clinical course and diagnosis of a patient with Cushing's disease complicated by pregnancy is described, and the anaesthetic management of trans-sphenoidal selective adenomectomy performed during the second trimester outlined. Problems included obesity, diabetes, hypertension and a suboptimal airway. Fibreoptic awake intubation and intravenous anaesthesia were used. Insulin requirements decreased substantially after surgery. Early administration of hydrocortisone after surgery avoided the risk of an addisonian crisis but delayed biochemical confirmation of a metabolic cure.

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KW - Cushing's syndrome

KW - Hypophysectomy

KW - Pituitary neoplasms

KW - Pregnancy

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ER -

Cushing's disease treated by trans-sphenoidal selective adenomectomy in mid-pregnancy

Abstract

ASJC Scopus subject areas

Keywords

UN SDGs

Access to Document

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