Abstract
Objective. To study the cluster of differentiation 8 population in the laryngeal mucosa of
patients with laryngeal carcinoma. To our knowledge this is the first paper to address this issue.
Methods. The study group included 40 patients with known laryngeal cancer who were scheduled
for laryngectomy. The control groups included 10 smokers and 10 non-smokers who
were scheduled for microlaryngeal surgery. Specimens from the three groups were processed
for histopathological and histochemical evaluation.
Results. In patients without cancer of the larynx, the number of cluster of differentiation 8
lymphocytes was greater in smokers than non-smokers. The number of cluster of differentiation
8 lymphocytes was greatest in smokers with laryngeal cancer, and the difference between
this group and the two control groups was statistically significant.
Conclusion. The study showed that smoking increased the number of cluster of differentiation
8 T-lymphocytes in the laryn
| Original language | English |
|---|---|
| Pages (from-to) | 1134-1134 |
| Number of pages | 1137 |
| Journal | Journal of Laryngology and Otology |
| Volume | 132 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 10 Dec 2018 |
