Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.

Superb K. Misra; F. Ohashi; Sabeel P. Valappil; Jonathan C. Knowles; I. Roy; S. Ravi P. Silva; Vehid Salih; Aldo R. Boccaccini

doi:10.1016/j.actbio.2009.09.023

Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.

Superb K. Misra, F. Ohashi, Sabeel P. Valappil, Jonathan C. Knowles, I. Roy, S. Ravi P. Silva, Vehid Salih, Aldo R. Boccaccini^*

^*Corresponding author for this work

Peninsula Dental School

Research output: Contribution to journal › Article › peer-review

Abstract

Poly(3-hydroxybutyrate) (P(3HB)) composites with bioactive glass particles and multiwall carbon nanotubes (MWCNTs) were prepared and used to identify whether the electrical properties of MWCNTs can be used to detect the bioactivity of P(3HB)/bioactive glass composites. The presence of MWCNTs (2-7 wt.%) increased the surface roughness of the composites. The presence of MWCNTs in low quantity enhanced MG-63 osteoblast-like cell attachment and proliferation compared to composites with higher concentration of MWCNTs. Current-voltage measurements demonstrated that the electrical resistance of the composites containing bioactive glass particles decreased over a 45-day immersion period in SBF, whereas composites without bioactive glass showed no significant change over the same period.

Original language	English
Pages (from-to)	735-742
Number of pages	0
Journal	Acta Biomater
Volume	6
Issue number	3
DOIs	https://doi.org/10.1016/j.actbio.2009.09.023
Publication status	Published - Mar 2010

Keywords

Absorption
Bone Substitutes
Cell Adhesion
Cell Culture Techniques
Cell Line
Cell Proliferation
Crystallization
Electric Conductivity
Glass
Humans
Hydroxybutyrates
Materials Testing
Nanotubes
Carbon
Osteoblasts
Particle Size
Polyesters
Porosity
Surface Properties
Tissue Engineering

Access to Document

10.1016/j.actbio.2009.09.023

Cite this

@article{349ed011ff7c41ba9e42eb0fababece4,

title = "Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.",

abstract = "Poly(3-hydroxybutyrate) (P(3HB)) composites with bioactive glass particles and multiwall carbon nanotubes (MWCNTs) were prepared and used to identify whether the electrical properties of MWCNTs can be used to detect the bioactivity of P(3HB)/bioactive glass composites. The presence of MWCNTs (2-7 wt.%) increased the surface roughness of the composites. The presence of MWCNTs in low quantity enhanced MG-63 osteoblast-like cell attachment and proliferation compared to composites with higher concentration of MWCNTs. Current-voltage measurements demonstrated that the electrical resistance of the composites containing bioactive glass particles decreased over a 45-day immersion period in SBF, whereas composites without bioactive glass showed no significant change over the same period.",

keywords = "Absorption, Bone Substitutes, Cell Adhesion, Cell Culture Techniques, Cell Line, Cell Proliferation, Crystallization, Electric Conductivity, Glass, Humans, Hydroxybutyrates, Materials Testing, Nanotubes, Carbon, Osteoblasts, Particle Size, Polyesters, Porosity, Surface Properties, Tissue Engineering",

author = "Misra, {Superb K.} and F. Ohashi and Valappil, {Sabeel P.} and Knowles, {Jonathan C.} and I. Roy and Silva, {S. Ravi P.} and Vehid Salih and Boccaccini, {Aldo R.}",

year = "2010",

month = mar,

doi = "10.1016/j.actbio.2009.09.023",

language = "English",

volume = "6",

pages = "735--742",

journal = "Acta Biomater",

issn = "1878-7568",

number = "3",

}

TY - JOUR

T1 - Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.

AU - Misra, Superb K.

AU - Ohashi, F.

AU - Valappil, Sabeel P.

AU - Knowles, Jonathan C.

AU - Roy, I.

AU - Silva, S. Ravi P.

AU - Salih, Vehid

AU - Boccaccini, Aldo R.

PY - 2010/3

Y1 - 2010/3

N2 - Poly(3-hydroxybutyrate) (P(3HB)) composites with bioactive glass particles and multiwall carbon nanotubes (MWCNTs) were prepared and used to identify whether the electrical properties of MWCNTs can be used to detect the bioactivity of P(3HB)/bioactive glass composites. The presence of MWCNTs (2-7 wt.%) increased the surface roughness of the composites. The presence of MWCNTs in low quantity enhanced MG-63 osteoblast-like cell attachment and proliferation compared to composites with higher concentration of MWCNTs. Current-voltage measurements demonstrated that the electrical resistance of the composites containing bioactive glass particles decreased over a 45-day immersion period in SBF, whereas composites without bioactive glass showed no significant change over the same period.

AB - Poly(3-hydroxybutyrate) (P(3HB)) composites with bioactive glass particles and multiwall carbon nanotubes (MWCNTs) were prepared and used to identify whether the electrical properties of MWCNTs can be used to detect the bioactivity of P(3HB)/bioactive glass composites. The presence of MWCNTs (2-7 wt.%) increased the surface roughness of the composites. The presence of MWCNTs in low quantity enhanced MG-63 osteoblast-like cell attachment and proliferation compared to composites with higher concentration of MWCNTs. Current-voltage measurements demonstrated that the electrical resistance of the composites containing bioactive glass particles decreased over a 45-day immersion period in SBF, whereas composites without bioactive glass showed no significant change over the same period.

KW - Absorption

KW - Bone Substitutes

KW - Cell Adhesion

KW - Cell Culture Techniques

KW - Cell Line

KW - Cell Proliferation

KW - Crystallization

KW - Electric Conductivity

KW - Glass

KW - Humans

KW - Hydroxybutyrates

KW - Materials Testing

KW - Nanotubes

KW - Carbon

KW - Osteoblasts

KW - Particle Size

KW - Polyesters

KW - Porosity

KW - Surface Properties

KW - Tissue Engineering

U2 - 10.1016/j.actbio.2009.09.023

DO - 10.1016/j.actbio.2009.09.023

M3 - Article

SN - 1878-7568

VL - 6

SP - 735

EP - 742

JO - Acta Biomater

JF - Acta Biomater

IS - 3

ER -

Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.

Abstract

Keywords

Access to Document

Fingerprint

Cite this