Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information

B Stanley; A Davis; R Jones; S Julious; D Ryan; D Jackson; D Halpin; H Pinnock; J Quint; K Khunti; L Heaney; P Oliver; S Siddiqui; A Kemppinen; F Appiagyei; E-J Roberts; A Hardjojo; V Carter; MV Melle; D Price

doi:10.1371/journal.pone.0258689

Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information

B Stanley, A Davis, R Jones, S Julious, D Ryan, D Jackson, D Halpin, H Pinnock, J Quint, K Khunti, L Heaney, P Oliver, S Siddiqui, A Kemppinen, F Appiagyei, E-J Roberts, A Hardjojo, V Carter, MV Melle, D Price

Peninsula Medical School

Research output: Contribution to journal › Article › peer-review

Abstract

Background Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a research database combining EHR data and bespoke patient questionnaire. We describe the demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19. Methods EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th August 2020, consenting patients aged 18–85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd January 2021. Findings From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases. Interpretation Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone.

Original language	English
Pages (from-to)	e0258689-e0258689
Number of pages	0
Journal	PLoS ONE
Volume	16
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0258689
Publication status	E-pub ahead of print - 19 Oct 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1371/journal.pone.0258689

Cite this

Stanley, B., Davis, A., Jones, R., Julious, S., Ryan, D., Jackson, D., Halpin, D., Pinnock, H., Quint, J., Khunti, K., Heaney, L., Oliver, P., Siddiqui, S., Kemppinen, A., Appiagyei, F., Roberts, E.-J., Hardjojo, A., Carter, V., Melle, MV., & Price, D. (2021). Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information. PLoS ONE, 16(10), e0258689-e0258689. Advance online publication. https://doi.org/10.1371/journal.pone.0258689

@article{87466d4fb0644147bcad2abccb09a730,

title = "Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information",

abstract = " Background Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a research database combining EHR data and bespoke patient questionnaire. We describe the demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19. Methods EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th August 2020, consenting patients aged 18–85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd January 2021. Findings From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases. Interpretation Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone. ",

author = "B Stanley and A Davis and R Jones and S Julious and D Ryan and D Jackson and D Halpin and H Pinnock and J Quint and K Khunti and L Heaney and P Oliver and S Siddiqui and A Kemppinen and F Appiagyei and E-J Roberts and A Hardjojo and V Carter and MV Melle and D Price",

year = "2021",

month = oct,

day = "19",

doi = "10.1371/journal.pone.0258689",

language = "English",

volume = "16",

pages = "e0258689--e0258689",

journal = "PLoS ONE",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "10",

}

Stanley, B, Davis, A, Jones, R, Julious, S, Ryan, D, Jackson, D, Halpin, D, Pinnock, H, Quint, J, Khunti, K, Heaney, L, Oliver, P, Siddiqui, S, Kemppinen, A, Appiagyei, F, Roberts, E-J, Hardjojo, A, Carter, V, Melle, MV & Price, D 2021, 'Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information', PLoS ONE, vol. 16, no. 10, pp. e0258689-e0258689. https://doi.org/10.1371/journal.pone.0258689

TY - JOUR

T1 - Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information

AU - Stanley, B

AU - Davis, A

AU - Jones, R

AU - Julious, S

AU - Ryan, D

AU - Jackson, D

AU - Halpin, D

AU - Pinnock, H

AU - Quint, J

AU - Khunti, K

AU - Heaney, L

AU - Oliver, P

AU - Siddiqui, S

AU - Kemppinen, A

AU - Appiagyei, F

AU - Roberts, E-J

AU - Hardjojo, A

AU - Carter, V

AU - Melle, MV

AU - Price, D

PY - 2021/10/19

Y1 - 2021/10/19

N2 - Background Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a research database combining EHR data and bespoke patient questionnaire. We describe the demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19. Methods EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th August 2020, consenting patients aged 18–85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd January 2021. Findings From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases. Interpretation Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone.

AB - Background Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a research database combining EHR data and bespoke patient questionnaire. We describe the demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19. Methods EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th August 2020, consenting patients aged 18–85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd January 2021. Findings From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases. Interpretation Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone.

U2 - 10.1371/journal.pone.0258689

DO - 10.1371/journal.pone.0258689

M3 - Article

SN - 1932-6203

VL - 16

SP - e0258689-e0258689

JO - PLoS ONE

JF - PLoS ONE

IS - 10

ER -

Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this