Cardiac glycosides are broad-spectrum senolytics

Ana Guerrero; Nicolás Herranz; Bin Sun; Verena Wagner; Suchira Gallage; Romain Guiho; Katharina Wolter; Joaquim Pombo; Elaine E. Irvine; Andrew J. Innes; Jodie Birch; Justyna Glegola; Saba Manshaei; Danijela Heide; Gopuraja Dharmalingam; Jule Harbig; Antoni Olona; Jacques Behmoaras; Daniel Dauch; Anthony G. Uren; Lars Zender; Santiago Vernia; Juan Pedro Martínez-Barbera; Mathias Heikenwalder; Dominic J. Withers; Jesús Gil

doi:10.1038/s42255-019-0122-z

Cardiac glycosides are broad-spectrum senolytics

Ana Guerrero, Nicolás Herranz, Bin Sun, Verena Wagner, Suchira Gallage, Romain Guiho, Katharina Wolter, Joaquim Pombo, Elaine E. Irvine, Andrew J. Innes, Jodie Birch, Justyna Glegola, Saba Manshaei, Danijela Heide, Gopuraja Dharmalingam, Jule Harbig, Antoni Olona, Jacques Behmoaras, Daniel Dauch, Anthony G. UrenLars Zender, Santiago Vernia, Juan Pedro Martínez-Barbera, Mathias Heikenwalder, Dominic J. Withers, Jesús Gil^*

^*Corresponding author for this work

School of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1074-1088
Number of pages	0
Journal	Nature Metabolism
Volume	1
Issue number	11
DOIs	https://doi.org/10.1038/s42255-019-0122-z
Publication status	E-pub ahead of print - 21 Oct 2019

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10.1038/s42255-019-0122-z

Cite this

Guerrero, A., Herranz, N., Sun, B., Wagner, V., Gallage, S., Guiho, R., Wolter, K., Pombo, J., Irvine, E. E., Innes, A. J., Birch, J., Glegola, J., Manshaei, S., Heide, D., Dharmalingam, G., Harbig, J., Olona, A., Behmoaras, J., Dauch, D., ... Gil, J. (2019). Cardiac glycosides are broad-spectrum senolytics. Nature Metabolism, 1(11), 1074-1088. Advance online publication. https://doi.org/10.1038/s42255-019-0122-z

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Guerrero, A, Herranz, N, Sun, B, Wagner, V, Gallage, S, Guiho, R, Wolter, K, Pombo, J, Irvine, EE, Innes, AJ, Birch, J, Glegola, J, Manshaei, S, Heide, D, Dharmalingam, G, Harbig, J, Olona, A, Behmoaras, J, Dauch, D, Uren, AG, Zender, L, Vernia, S, Martínez-Barbera, JP, Heikenwalder, M, Withers, DJ & Gil, J 2019, 'Cardiac glycosides are broad-spectrum senolytics', Nature Metabolism, vol. 1, no. 11, pp. 1074-1088. https://doi.org/10.1038/s42255-019-0122-z

TY - JOUR

T1 - Cardiac glycosides are broad-spectrum senolytics

AU - Guerrero, Ana

AU - Herranz, Nicolás

AU - Sun, Bin

AU - Wagner, Verena

AU - Gallage, Suchira

AU - Guiho, Romain

AU - Wolter, Katharina

AU - Pombo, Joaquim

AU - Irvine, Elaine E.

AU - Innes, Andrew J.

AU - Birch, Jodie

AU - Glegola, Justyna

AU - Manshaei, Saba

AU - Heide, Danijela

AU - Dharmalingam, Gopuraja

AU - Harbig, Jule

AU - Olona, Antoni

AU - Behmoaras, Jacques

AU - Dauch, Daniel

AU - Uren, Anthony G.

AU - Zender, Lars

AU - Vernia, Santiago

AU - Martínez-Barbera, Juan Pedro

AU - Heikenwalder, Mathias

AU - Withers, Dominic J.

AU - Gil, Jesús

PY - 2019/10/21

Y1 - 2019/10/21

U2 - 10.1038/s42255-019-0122-z

DO - 10.1038/s42255-019-0122-z

M3 - Article

SN - 2522-5812

VL - 1

SP - 1074

EP - 1088

JO - Nature Metabolism

JF - Nature Metabolism

IS - 11

ER -