Avoiding kidney damage in ICU sedation with sevoflurane: use isoflurane instead

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Abstract

Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.

Original languageEnglish
Pages (from-to)7-10
Number of pages4
JournalBritish Journal of Anaesthesia
Volume129
Issue number1
DOIs
Publication statusPublished - Jul 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Keywords

  • acute kidney injury
  • diabetes insipidus
  • isoflurane
  • nephrotoxicity
  • sedation
  • sevoflurane

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