Abstract
The causal hypothesis of quality of life predicts that questionnaire items measuring the construct of problems are more sensitive to change in a clinical trial compared with those measuring the construct of evaluations. This prediction was confirmed in 2 clinical trials of patients with asthma who were administered salmeterol in comparison with another treatment. These and other data show that whether a significant effect is obtained in a clinical trial, and the size of any effect, depend on the properties of the questionnaire used to assess quality of life. Quantitative assessments of improvement in quality of life should be treated with caution in economic evaluations.
| Original language | English |
|---|---|
| Pages (from-to) | 324-329 |
| Number of pages | 0 |
| Journal | PharmacoEconomics |
| Volume | 6 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 1994 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Albuterol
- Asthma
- Humans
- Longitudinal Studies
- Quality of Life
- Surveys and Questionnaires
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