Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

Z Li; C Wang; Z Wang; Chenggang Zhu; J Li; Tian Sha; Lixiang Ma; Chao Gao; Yi Yang; Y Sun; J Wang; X Sun; C Lu; Marian Difiglia; Yanai Mei; C Ding; Shouqing Luo; Yongjun Dang; Y Ding; Yiyan Fei; B Lu

doi:10.1038/s41586-019-1722-1

Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

Z Li
, C Wang
, Z Wang
, Chenggang Zhu
, J Li
, Tian Sha
, Lixiang Ma
, Chao Gao
, Yi Yang
, Y Sun
, J Wang
, X Sun
, C Lu
, Marian Difiglia
, Yanai Mei
, C Ding
, Shouqing Luo
, Yongjun Dang
, Y Ding
, Yiyan Fei

B Lu

Peninsula Medical School

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	203-209
Number of pages	0
Journal	Nature
Volume	575
Issue number	7781
Early online date	30 Oct 2019
DOIs	https://doi.org/10.1038/s41586-019-1722-1
Publication status	Published - 30 Oct 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/s41586-019-1722-1

Extended-Fig 7Other version, 7.53 MBLicence: CC BY-NC
Extended-Fig 1Other version, 3.93 MBLicence: CC BY-NC
Extended-Fig 2Other version, 946 KBLicence: CC BY-NC
Extended-Fig 3Other version, 6.34 MBLicence: CC BY-NC
Extended-Fig 4Other version, 2.67 MBLicence: CC BY-NC
Extended-Fig 5Other version, 1.14 MBLicence: CC BY-NC
Extended-Fig 6Other version, 3.05 MBLicence: CC BY-NC
Extended-Fig 8Other version, 2.99 MBLicence: CC BY-NC
Extended-Fig 9Other version, 5.69 MBLicence: CC BY-NC
Extended-Table 1Other version, 436 KBLicence: CC BY-NC
HTT-LC3 linker accepted articleAccepted author manuscript, 24.8 MBLicence: CC BY-NC

Cite this

@article{acb890278b52443c9b60ea5ba41d7f97,

title = "Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds",

author = "Z Li and C Wang and Z Wang and Chenggang Zhu and J Li and Tian Sha and Lixiang Ma and Chao Gao and Yi Yang and Y Sun and J Wang and X Sun and C Lu and Marian Difiglia and Yanai Mei and C Ding and Shouqing Luo and Yongjun Dang and Y Ding and Yiyan Fei and B Lu",

year = "2019",

month = oct,

day = "30",

doi = "10.1038/s41586-019-1722-1",

language = "English",

volume = "575",

pages = "203--209",

journal = "Nature",

issn = "0028-0836",

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number = "7781",

}

TY - JOUR

T1 - Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

AU - Li, Z

AU - Wang, C

AU - Wang, Z

AU - Zhu, Chenggang

AU - Li, J

AU - Sha, Tian

AU - Ma, Lixiang

AU - Gao, Chao

AU - Yang, Yi

AU - Sun, Y

AU - Wang, J

AU - Sun, X

AU - Lu, C

AU - Difiglia, Marian

AU - Mei, Yanai

AU - Ding, C

AU - Luo, Shouqing

AU - Dang, Yongjun

AU - Ding, Y

AU - Fei, Yiyan

AU - Lu, B

PY - 2019/10/30

Y1 - 2019/10/30

UR - https://pearl.plymouth.ac.uk/pms-research/913/

U2 - 10.1038/s41586-019-1722-1

DO - 10.1038/s41586-019-1722-1

M3 - Article

SN - 0028-0836

VL - 575

SP - 203

EP - 209

JO - Nature

JF - Nature

IS - 7781

ER -

Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

UN SDGs

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