Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

Carolyn S. Calfee; Kevin L. Delucchi; Pratik Sinha; Michael A. Matthay; Jonathan Hackett; Manu Shankar-Hari; Cliona McDowell; John G. Laffey; CM O'Kane; Daniel F. McAuley; AJ Johnston; Archana Paikray; Cat Yates; Petra Polgarova; Esther Price; Amy McInerney; Katarzyna Zamoscik; Ged Dempsey; Colette Seasman; Lynn Gilfeather; Noel Hemmings; S O'Kane; P Johnston; Lukas Pokorny; Chris Nutt; Orla O'Neill; Prashast Prashast; Chris Smalley; Reni Jacob; James O'Rourke; Syed Farjad Sultan; Carole Schilling; Gavin D. Perkins; Teresa Melody; Keith Couper; Ron Daniels; Fang Gao; Julian Hull; Timothy Gould; Matthew Thomas; Katie Sweet; Dorothy Breen; Emer Neau; Willis J. Peel; Catherine Jardine; Paul Jefferson; Stephen E. Wright; Kayla Harris; Matthew Thomas; Sarah Hierons; John G. Laffey; Amy McInerney; L Camporota; K Lei; S Kaul; M Chibvuri; A Gratrix; R Bennett; V Martinson; L Sleight; N Smith; PA Hopkins; D Hadfield; S Casboult; F Wade-Smith; J Dawson; C Mellis; Kayla Harris; G Parsons; S Helyar; AR Bodenham; S Elliot; Z Beardow; S Birch; B Marsh; Daniel Martin; A Dhrampal; M Rosbergen; S Webb; F Bottrill; H Reschreiter; H Barcraft-Barnes; J Camsooksai; A Johnston; A Clarkson; C Bentley; L Cooper; Y Qui; N Mitchell; R Carrera; Whiteho

doi:10.1016/s2213-2600(18)30177-2

Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

Carolyn S. Calfee^*
, Kevin L. Delucchi
, Pratik Sinha
, Michael A. Matthay
, Jonathan Hackett
, Manu Shankar-Hari
, Cliona McDowell
, John G. Laffey
, CM O'Kane
, Daniel F. McAuley
, AJ Johnston
, Archana Paikray
, Cat Yates
, Petra Polgarova
, Esther Price
, Amy McInerney
, Katarzyna Zamoscik
, Ged Dempsey
, Colette Seasman
, Lynn Gilfeather

Noel Hemmings, S O'Kane, P Johnston, Lukas Pokorny, Chris Nutt, Orla O'Neill, Prashast Prashast, Chris Smalley, Reni Jacob, James O'Rourke, Syed Farjad Sultan, Carole Schilling, Gavin D. Perkins, Teresa Melody, Keith Couper, Ron Daniels, Fang Gao, Julian Hull, Timothy Gould, Matthew Thomas, Katie Sweet, Dorothy Breen, Emer Neau, Willis J. Peel, Catherine Jardine, Paul Jefferson, Stephen E. Wright, Kayla Harris, Matthew Thomas, Sarah Hierons, John G. Laffey, Amy McInerney, L Camporota, K Lei, S Kaul, M Chibvuri, A Gratrix, R Bennett, V Martinson, L Sleight, N Smith, PA Hopkins, D Hadfield, S Casboult, F Wade-Smith, J Dawson, C Mellis, Kayla Harris, G Parsons, S Helyar, AR Bodenham, S Elliot, Z Beardow, S Birch, B Marsh, Daniel Martin, A Dhrampal, M Rosbergen, S Webb, F Bottrill, H Reschreiter, H Barcraft-Barnes, J Camsooksai, A Johnston, A Clarkson, C Bentley, L Cooper, Y Qui, N Mitchell, R Carrera, Whiteho

^*Corresponding author for this work

Faculty of Health

University of California at San Francisco
Queen's University Belfast
King's College London
Royal Victoria Hospital Belfast
University of Galway
University of Toronto

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	691-698
Number of pages	0
Journal	The Lancet Respiratory Medicine
Volume	6
Issue number	9
DOIs	https://doi.org/10.1016/s2213-2600(18)30177-2
Publication status	Published - Sept 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/s2213-2600(18)30177-2

Cite this

Calfee, C. S., Delucchi, K. L., Sinha, P., Matthay, M. A., Hackett, J., Shankar-Hari, M., McDowell, C., Laffey, J. G., O'Kane, CM., McAuley, D. F., Johnston, AJ., Paikray, A., Yates, C., Polgarova, P., Price, E., McInerney, A., Zamoscik, K., Dempsey, G., Seasman, C., ... Whiteho (2018). Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. The Lancet Respiratory Medicine, 6(9), 691-698. https://doi.org/10.1016/s2213-2600(18)30177-2

@article{c61da4e3f25b4bb2988dcd3f5bd48128,

title = "Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial",

author = "Calfee, \{Carolyn S.\} and Delucchi, \{Kevin L.\} and Pratik Sinha and Matthay, \{Michael A.\} and Jonathan Hackett and Manu Shankar-Hari and Cliona McDowell and Laffey, \{John G.\} and CM O'Kane and McAuley, \{Daniel F.\} and AJ Johnston and Archana Paikray and Cat Yates and Petra Polgarova and Esther Price and Amy McInerney and Katarzyna Zamoscik and Ged Dempsey and Colette Seasman and Lynn Gilfeather and Noel Hemmings and S O'Kane and P Johnston and Lukas Pokorny and Chris Nutt and Orla O'Neill and Prashast Prashast and Chris Smalley and Reni Jacob and James O'Rourke and Sultan, \{Syed Farjad\} and Carole Schilling and Perkins, \{Gavin D.\} and Teresa Melody and Keith Couper and Ron Daniels and Fang Gao and Julian Hull and Timothy Gould and Matthew Thomas and Katie Sweet and Dorothy Breen and Emer Neau and Peel, \{Willis J.\} and Catherine Jardine and Paul Jefferson and Wright, \{Stephen E.\} and Kayla Harris and Matthew Thomas and Sarah Hierons and Laffey, \{John G.\} and Amy McInerney and L Camporota and K Lei and S Kaul and M Chibvuri and A Gratrix and R Bennett and V Martinson and L Sleight and N Smith and PA Hopkins and D Hadfield and S Casboult and F Wade-Smith and J Dawson and C Mellis and Kayla Harris and G Parsons and S Helyar and AR Bodenham and S Elliot and Z Beardow and S Birch and B Marsh and Daniel Martin and A Dhrampal and M Rosbergen and S Webb and F Bottrill and H Reschreiter and H Barcraft-Barnes and J Camsooksai and A Johnston and A Clarkson and C Bentley and L Cooper and Y Qui and N Mitchell and R Carrera and Whiteho",

year = "2018",

month = sep,

doi = "10.1016/s2213-2600(18)30177-2",

language = "English",

volume = "6",

pages = "691--698",

journal = "The Lancet Respiratory Medicine",

issn = "2213-2600",

publisher = "Elsevier Ltd.",

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Calfee, CS, Delucchi, KL, Sinha, P, Matthay, MA, Hackett, J, Shankar-Hari, M, McDowell, C, Laffey, JG, O'Kane, CM, McAuley, DF, Johnston, AJ, Paikray, A, Yates, C, Polgarova, P, Price, E, McInerney, A, Zamoscik, K, Dempsey, G, Seasman, C, Gilfeather, L, Hemmings, N, O'Kane, S, Johnston, P, Pokorny, L, Nutt, C, O'Neill, O, Prashast, P, Smalley, C, Jacob, R, O'Rourke, J, Sultan, SF, Schilling, C, Perkins, GD, Melody, T, Couper, K, Daniels, R, Gao, F, Hull, J, Gould, T, Thomas, M, Sweet, K, Breen, D, Neau, E, Peel, WJ, Jardine, C, Jefferson, P, Wright, SE, Harris, K, Thomas, M, Hierons, S, Laffey, JG, McInerney, A, Camporota, L, Lei, K, Kaul, S, Chibvuri, M, Gratrix, A, Bennett, R, Martinson, V, Sleight, L, Smith, N, Hopkins, PA, Hadfield, D, Casboult, S, Wade-Smith, F, Dawson, J, Mellis, C, Harris, K, Parsons, G, Helyar, S, Bodenham, AR, Elliot, S, Beardow, Z, Birch, S, Marsh, B, Martin, D, Dhrampal, A, Rosbergen, M, Webb, S, Bottrill, F, Reschreiter, H, Barcraft-Barnes, H, Camsooksai, J, Johnston, A, Clarkson, A, Bentley, C, Cooper, L, Qui, Y, Mitchell, N, Carrera, R & Whiteho 2018, 'Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial', The Lancet Respiratory Medicine, vol. 6, no. 9, pp. 691-698. https://doi.org/10.1016/s2213-2600(18)30177-2

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T1 - Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

AU - Calfee, Carolyn S.

AU - Delucchi, Kevin L.

AU - Sinha, Pratik

AU - Matthay, Michael A.

AU - Hackett, Jonathan

AU - Shankar-Hari, Manu

AU - McDowell, Cliona

AU - Laffey, John G.

AU - O'Kane, CM

AU - McAuley, Daniel F.

AU - Johnston, AJ

AU - Paikray, Archana

AU - Yates, Cat

AU - Polgarova, Petra

AU - Price, Esther

AU - McInerney, Amy

AU - Zamoscik, Katarzyna

AU - Dempsey, Ged

AU - Seasman, Colette

AU - Gilfeather, Lynn

AU - Hemmings, Noel

AU - O'Kane, S

AU - Johnston, P

AU - Pokorny, Lukas

AU - Nutt, Chris

AU - O'Neill, Orla

AU - Prashast, Prashast

AU - Smalley, Chris

AU - Jacob, Reni

AU - O'Rourke, James

AU - Sultan, Syed Farjad

AU - Schilling, Carole

AU - Perkins, Gavin D.

AU - Melody, Teresa

AU - Couper, Keith

AU - Daniels, Ron

AU - Gao, Fang

AU - Hull, Julian

AU - Gould, Timothy

AU - Thomas, Matthew

AU - Sweet, Katie

AU - Breen, Dorothy

AU - Neau, Emer

AU - Peel, Willis J.

AU - Jardine, Catherine

AU - Jefferson, Paul

AU - Wright, Stephen E.

AU - Harris, Kayla

AU - Thomas, Matthew

AU - Hierons, Sarah

AU - Laffey, John G.

AU - McInerney, Amy

AU - Camporota, L

AU - Lei, K

AU - Kaul, S

AU - Chibvuri, M

AU - Gratrix, A

AU - Bennett, R

AU - Martinson, V

AU - Sleight, L

AU - Smith, N

AU - Hopkins, PA

AU - Hadfield, D

AU - Casboult, S

AU - Wade-Smith, F

AU - Dawson, J

AU - Mellis, C

AU - Harris, Kayla

AU - Parsons, G

AU - Helyar, S

AU - Bodenham, AR

AU - Elliot, S

AU - Beardow, Z

AU - Birch, S

AU - Marsh, B

AU - Martin, Daniel

AU - Dhrampal, A

AU - Rosbergen, M

AU - Webb, S

AU - Bottrill, F

AU - Reschreiter, H

AU - Barcraft-Barnes, H

AU - Camsooksai, J

AU - Johnston, A

AU - Clarkson, A

AU - Bentley, C

AU - Cooper, L

AU - Qui, Y

AU - Mitchell, N

AU - Carrera, R

AU - Whiteho, null

PY - 2018/9

Y1 - 2018/9

U2 - 10.1016/s2213-2600(18)30177-2

DO - 10.1016/s2213-2600(18)30177-2

M3 - Article

SN - 2213-2600

VL - 6

SP - 691

EP - 698

JO - The Lancet Respiratory Medicine

JF - The Lancet Respiratory Medicine

IS - 9

ER -