A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly

PR Hodgkins; A Kriss; S Boyd; K Chong; D Thompson; DS Taylor; I Russell-Eggitt; CM Harris

doi:10.1017/s0012162200000098

A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly

PR Hodgkins, A Kriss, S Boyd, K Chong, D Thompson, DS Taylor, I Russell-Eggitt, CM Harris

School of Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

EEG, flash electroretinogram (ERG), and visual evoked potential (VEP) findings are described in eight children with classical lissencephaly (six girls, two boys), with a mean age of 17.6 months (range 2 to 60 months). The EEG shows typically high-voltage activity. Eye movements were formally recorded in two patients, and both showed features associated with oculomotor apraxia. The ERG and VEP to flash stimulation were normal in all cases. Two subjects had pattern reversal stimulation, and their pattern VEPs were within normal limits. Some patients with lissencephaly may appear to have delayed visual maturation on first presentation, and EEG and eye movement studies are valuable in indicating neurological deficiency at an early stage in these subjects.

Original language	English
Pages (from-to)	48-52
Number of pages	0
Journal	Developmental Medicine & Child Neurology
Volume	42
Issue number	1
DOIs	https://doi.org/10.1017/s0012162200000098 https://doi.org/10.1111/j.1469-8749.2000.tb00024.x
Publication status	Published - Jan 2000

Keywords

Apraxias
Brain
Child
Preschool
Electroencephalography
Electroretinography
Evoked Potentials
Visual
Female
Humans
Infant
Male
Nervous System Malformations
Ocular Motility Disorders
Oculomotor Muscles
Retrospective Studies

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Hodgkins, PR., Kriss, A., Boyd, S., Chong, K., Thompson, D., Taylor, DS., Russell-Eggitt, I., & Harris, CM. (2000). A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly. Developmental Medicine & Child Neurology, 42(1), 48-52. https://doi.org/10.1017/s0012162200000098, https://doi.org/10.1111/j.1469-8749.2000.tb00024.x

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title = "A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly",

abstract = "EEG, flash electroretinogram (ERG), and visual evoked potential (VEP) findings are described in eight children with classical lissencephaly (six girls, two boys), with a mean age of 17.6 months (range 2 to 60 months). The EEG shows typically high-voltage activity. Eye movements were formally recorded in two patients, and both showed features associated with oculomotor apraxia. The ERG and VEP to flash stimulation were normal in all cases. Two subjects had pattern reversal stimulation, and their pattern VEPs were within normal limits. Some patients with lissencephaly may appear to have delayed visual maturation on first presentation, and EEG and eye movement studies are valuable in indicating neurological deficiency at an early stage in these subjects.",

keywords = "Apraxias, Brain, Child, Preschool, Electroencephalography, Electroretinography, Evoked Potentials, Visual, Female, Humans, Infant, Male, Nervous System Malformations, Ocular Motility Disorders, Oculomotor Muscles, Retrospective Studies",

author = "PR Hodgkins and A Kriss and S Boyd and K Chong and D Thompson and DS Taylor and I Russell-Eggitt and CM Harris",

year = "2000",

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doi = "10.1017/s0012162200000098",

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Hodgkins, PR, Kriss, A, Boyd, S, Chong, K, Thompson, D, Taylor, DS, Russell-Eggitt, I & Harris, CM 2000, 'A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly', Developmental Medicine & Child Neurology, vol. 42, no. 1, pp. 48-52. https://doi.org/10.1017/s0012162200000098, https://doi.org/10.1111/j.1469-8749.2000.tb00024.x

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T1 - A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly

AU - Hodgkins, PR

AU - Kriss, A

AU - Boyd, S

AU - Chong, K

AU - Thompson, D

AU - Taylor, DS

AU - Russell-Eggitt, I

AU - Harris, CM

PY - 2000/1

Y1 - 2000/1

N2 - EEG, flash electroretinogram (ERG), and visual evoked potential (VEP) findings are described in eight children with classical lissencephaly (six girls, two boys), with a mean age of 17.6 months (range 2 to 60 months). The EEG shows typically high-voltage activity. Eye movements were formally recorded in two patients, and both showed features associated with oculomotor apraxia. The ERG and VEP to flash stimulation were normal in all cases. Two subjects had pattern reversal stimulation, and their pattern VEPs were within normal limits. Some patients with lissencephaly may appear to have delayed visual maturation on first presentation, and EEG and eye movement studies are valuable in indicating neurological deficiency at an early stage in these subjects.

AB - EEG, flash electroretinogram (ERG), and visual evoked potential (VEP) findings are described in eight children with classical lissencephaly (six girls, two boys), with a mean age of 17.6 months (range 2 to 60 months). The EEG shows typically high-voltage activity. Eye movements were formally recorded in two patients, and both showed features associated with oculomotor apraxia. The ERG and VEP to flash stimulation were normal in all cases. Two subjects had pattern reversal stimulation, and their pattern VEPs were within normal limits. Some patients with lissencephaly may appear to have delayed visual maturation on first presentation, and EEG and eye movement studies are valuable in indicating neurological deficiency at an early stage in these subjects.

KW - Apraxias

KW - Brain

KW - Child

KW - Preschool

KW - Electroencephalography

KW - Electroretinography

KW - Evoked Potentials

KW - Visual

KW - Female

KW - Humans

KW - Infant

KW - Male

KW - Nervous System Malformations

KW - Ocular Motility Disorders

KW - Oculomotor Muscles

KW - Retrospective Studies

U2 - 10.1017/s0012162200000098

DO - 10.1017/s0012162200000098

M3 - Article

SN - 0012-1622

VL - 42

SP - 48

EP - 52

JO - Developmental Medicine & Child Neurology

JF - Developmental Medicine & Child Neurology

IS - 1

ER -

A study of EEG, electroretinogram, visual evoked potential, and eye movements in classical lissencephaly

Abstract

Keywords

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