A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes

Richard Hill; Ravi Kiran Reddy Kalathur; Sergio Callejas; Laura Colaço; Ricardo Brandão; Beatriz Serelde; Antonio Cebriá; Carmen Blanco-Aparicio; Joaquín Pastor; Matthias Futschik; Ana Dopazo; Wolfgang Link

doi:10.1186/s13058-014-0482-y

A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes

Richard Hill, Ravi Kiran Reddy Kalathur, Sergio Callejas, Laura Colaço, Ricardo Brandão, Beatriz Serelde, Antonio Cebriá, Carmen Blanco-Aparicio, Joaquín Pastor, Matthias Futschik, Ana Dopazo, Wolfgang Link^*

^*Corresponding author for this work

School of Biomedical Sciences

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Original language	English
Number of pages	0
Journal	Breast Cancer Research
Volume	16
Issue number	6
DOIs	https://doi.org/10.1186/s13058-014-0482-y
Publication status	Published - Dec 2014

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10.1186/s13058-014-0482-y

A novel phosphatidylinositol 3-kinase (PI3K) inhibitor

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Hill, R., Kalathur, R. K. R., Callejas, S., Colaço, L., Brandão, R., Serelde, B., Cebriá, A., Blanco-Aparicio, C., Pastor, J., Futschik, M., Dopazo, A., & Link, W. (2014). A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes. Breast Cancer Research, 16(6). https://doi.org/10.1186/s13058-014-0482-y

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title = "A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes",

author = "Richard Hill and Kalathur, {Ravi Kiran Reddy} and Sergio Callejas and Laura Cola{\c c}o and Ricardo Brand{\~a}o and Beatriz Serelde and Antonio Cebri{\'a} and Carmen Blanco-Aparicio and Joaqu{\'i}n Pastor and Matthias Futschik and Ana Dopazo and Wolfgang Link",

year = "2014",

month = dec,

doi = "10.1186/s13058-014-0482-y",

language = "English",

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journal = "Breast Cancer Research",

issn = "1465-5411",

publisher = "BioMed Central Ltd.",

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Hill, R, Kalathur, RKR, Callejas, S, Colaço, L, Brandão, R, Serelde, B, Cebriá, A, Blanco-Aparicio, C, Pastor, J, Futschik, M, Dopazo, A & Link, W 2014, 'A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes', Breast Cancer Research, vol. 16, no. 6. https://doi.org/10.1186/s13058-014-0482-y

A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes. / Hill, Richard; Kalathur, Ravi Kiran Reddy; Callejas, Sergio et al.
In: Breast Cancer Research, Vol. 16, No. 6, 12.2014.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes

AU - Hill, Richard

AU - Kalathur, Ravi Kiran Reddy

AU - Callejas, Sergio

AU - Colaço, Laura

AU - Brandão, Ricardo

AU - Serelde, Beatriz

AU - Cebriá, Antonio

AU - Blanco-Aparicio, Carmen

AU - Pastor, Joaquín

AU - Futschik, Matthias

AU - Dopazo, Ana

AU - Link, Wolfgang

PY - 2014/12

Y1 - 2014/12

UR - https://pearl.plymouth.ac.uk/context/bhs-research/article/1155/viewcontent/A_20novel_20phosphatidylinositol_203_kinase_20_PI3K__20inhibitor_20directs_20a_20potent_20FOXO_dependent__20p53_independent_20cell_20cycle_20arrest_20phenotype_20characterized_20by_20the_20differential_20induction_20of_20a_20subset_20of_20FOXO_regulated_20genes.pdf

U2 - 10.1186/s13058-014-0482-y

DO - 10.1186/s13058-014-0482-y

M3 - Article

SN - 1465-5411

VL - 16

JO - Breast Cancer Research

JF - Breast Cancer Research

IS - 6

ER -

A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes

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