Abstract
Anaesthesia induced with remimazolam and a fentanyl-series opioid can be reversed with flumazenil and naloxone. Concomitant paralysis with rocuronium can facilitate tracheal intubation whilst being reversible with sugammadex. Together, this combination might offer full reversibility of a ‘routine’ or a ‘rapid-sequence’ induction anaesthesia. Whether this is useful, or even safe, requires careful evaluation.
| Original language | English |
|---|---|
| Pages (from-to) | 16-18 |
| Number of pages | 3 |
| Journal | British Journal of Anaesthesia |
| Volume | 133 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2024 |
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Keywords
- flumazenil
- naloxone
- neuromuscular block
- rapid sequence induction
- remimazolam
- reversal
- rocuronium
- sugammadex
- Benzodiazepines/pharmacology
- Intubation, Intratracheal/methods
- Analgesics, Opioid
- Humans
- Fentanyl
- Rapid Sequence Induction and Intubation/methods
- Neuromuscular Nondepolarizing Agents/antagonists & inhibitors
- Rocuronium/administration & dosage
- Naloxone
- Sugammadex/pharmacology
- Androstanols/antagonists & inhibitors