A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound

R Payne; C Smith; S Hill; T Liddicoat; M Gill

A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound

R Payne
, C Smith
, S Hill
, T Liddicoat
, M Gill

School of Geography, Earth and Environmental Sciences

Research output: Contribution to journal › Conference proceedings published in a journal › peer-review

Abstract

Data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers was compared using plasma extracts spiked with an anti-cancer compound. A standard curve was prepared over a range of 0.6 to 1600 ng/ml was claimed using a deuterated internal standard. A solution of the anticancer compound was prepared at a concentration of 10μg/ml in methanol. The results show that it is apparent that the API-4000 is more sensitive by a value of about 3-4 when the compound is the anticancer compound that was run.

Original language	English
Pages (from-to)	649-650
Number of pages	0
Journal	Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
Volume	0
Issue number	0
Publication status	Published - 1 Dec 2002

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SDG 3 Good Health and Well-being

Cite this

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title = "A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound",

abstract = "Data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers was compared using plasma extracts spiked with an anti-cancer compound. A standard curve was prepared over a range of 0.6 to 1600 ng/ml was claimed using a deuterated internal standard. A solution of the anticancer compound was prepared at a concentration of 10μg/ml in methanol. The results show that it is apparent that the API-4000 is more sensitive by a value of about 3-4 when the compound is the anticancer compound that was run.",

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A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound. / Payne, R; Smith, C; Hill, S et al.
In: Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, Vol. 0, No. 0, 01.12.2002, p. 649-650.

Research output: Contribution to journal › Conference proceedings published in a journal › peer-review

TY - JOUR

T1 - A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound

AU - Payne, R

AU - Smith, C

AU - Hill, S

AU - Liddicoat, T

AU - Gill, M

PY - 2002/12/1

Y1 - 2002/12/1

N2 - Data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers was compared using plasma extracts spiked with an anti-cancer compound. A standard curve was prepared over a range of 0.6 to 1600 ng/ml was claimed using a deuterated internal standard. A solution of the anticancer compound was prepared at a concentration of 10μg/ml in methanol. The results show that it is apparent that the API-4000 is more sensitive by a value of about 3-4 when the compound is the anticancer compound that was run.

AB - Data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers was compared using plasma extracts spiked with an anti-cancer compound. A standard curve was prepared over a range of 0.6 to 1600 ng/ml was claimed using a deuterated internal standard. A solution of the anticancer compound was prepared at a concentration of 10μg/ml in methanol. The results show that it is apparent that the API-4000 is more sensitive by a value of about 3-4 when the compound is the anticancer compound that was run.

M3 - Conference proceedings published in a journal

VL - 0

SP - 649

EP - 650

JO - Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics

JF - Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics

IS - 0

ER -

A comparison of the data generated on the Sciex API-3000 and Sciex API-4000 triple quadrupole mass spectrometers using plasma extracts spiked with an anti-cancer compound

Abstract

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