A comparison of glutathione reductase and glutathione peroxidase activities in patients with rheumatoid arthritis and healthy adults.

J. Braven*, N. Ansari, D. P. Figgitt, A. Fisher, Christine Luders, P. Hickling, Mary Whittaker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A 30% increase in erythrocyte glutathione peroxidase (GP) activity was found in patients with rheumatoid arthritis when compared with healthy controls (p = 0.001) whereas the increase in glutathione reductase (GR) was statistically insignificant. No correlation was found between the activities of the enzymes and the erythrocyte sedimentation rate (ESR). The enzyme activities were independent of age, sex, or type of drug treatment of the patients. A possible interpretation of the results is presented.
Original languageEnglish
Pages (from-to)212-215
Number of pages0
JournalBr J Rheumatol
Volume28
Issue number3
DOIs
Publication statusPublished - Jun 1989

Keywords

  • Adult
  • Arthritis
  • Rheumatoid
  • Blood Sedimentation
  • Glutathione Peroxidase
  • Glutathione Reductase
  • Humans
  • Middle Aged
  • Reference Values

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