A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers

Ben Hicks; Sanna Read; Bo Hu; Raphael Wittenberg; Amanda Grahamslaw; Anomita Karim; Evelyn Martin; Eleanor Nuzum; Jacob Reichental; Alice Russell; Elaine Siddle; Bryony Storey; Eva Tipping; Kate Baxter; Yvonne Birks; Carol Brayne; Nicola Brimblecombe; Margaret Dangoor; Josie Dixon; Kate Gridley; Peter R. Harris; Martin Knapp; Eleanor Miles; Rotem Perach; Louise Robinson; Jennifer Rusted; Rob Stewart; Alan J. Thomas; Sube Banerjee

doi:10.1002/trc2.12236

A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers

Ben Hicks, Sanna Read, Bo Hu, Raphael Wittenberg, Amanda Grahamslaw, Anomita Karim, Evelyn Martin, Eleanor Nuzum, Jacob Reichental, Alice Russell, Elaine Siddle, Bryony Storey, Eva Tipping, Kate Baxter, Yvonne Birks, Carol Brayne, Nicola Brimblecombe, Margaret Dangoor, Josie Dixon, Kate GridleyPeter R. Harris, Martin Knapp, Eleanor Miles, Rotem Perach, Louise Robinson, Jennifer Rusted, Rob Stewart, Alan J. Thomas, Sube Banerjee^*

^*Corresponding author for this work

Faculty of Health

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction: COVID-19 has impacted people with dementia and their family carers, yet little is known about effects on overall quality of life. Methods: In a UK cohort study, pre- and post-pandemic data were collected from 114 carers and 93 recently diagnosed people with dementia. Latent growth curve modeling examined change in quality of life. Results: Carers reported significant decline in quality of life, although no change was demonstrated by people with dementia. In multivariable analyses, higher levels of cognitive impairment, deprivation, study site, and lower number of memory clinic contacts were associated with greater decline in carer quality of life. Discussion: Maintaining life quality for people with dementia during the pandemic appears to have come at the expense of their family carers. This inequity has fallen hardest on those caring for people with more severe dementia, in deprived areas, and with least support from memory services. These effects may be prevented or reversed by post-diagnostic care.

Original language	English
Article number	e12236
Journal	Alzheimer's and Dementia: Translational Research and Clinical Interventions
Volume	8
Issue number	1
DOIs	https://doi.org/10.1002/trc2.12236
Publication status	Published - 2022

ASJC Scopus subject areas

Neurology (clinical)
Psychiatry and Mental Health

Keywords

cohort study
COVID-19
dementia
inequalities
inequities
post-diagnostic care
quality of life

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10.1002/trc2.12236

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Hicks, B., Read, S., Hu, B., Wittenberg, R., Grahamslaw, A., Karim, A., Martin, E., Nuzum, E., Reichental, J., Russell, A., Siddle, E., Storey, B., Tipping, E., Baxter, K., Birks, Y., Brayne, C., Brimblecombe, N., Dangoor, M., Dixon, J., ... Banerjee, S. (2022). A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 8(1), Article e12236. https://doi.org/10.1002/trc2.12236

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title = "A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers",

abstract = "Introduction: COVID-19 has impacted people with dementia and their family carers, yet little is known about effects on overall quality of life. Methods: In a UK cohort study, pre- and post-pandemic data were collected from 114 carers and 93 recently diagnosed people with dementia. Latent growth curve modeling examined change in quality of life. Results: Carers reported significant decline in quality of life, although no change was demonstrated by people with dementia. In multivariable analyses, higher levels of cognitive impairment, deprivation, study site, and lower number of memory clinic contacts were associated with greater decline in carer quality of life. Discussion: Maintaining life quality for people with dementia during the pandemic appears to have come at the expense of their family carers. This inequity has fallen hardest on those caring for people with more severe dementia, in deprived areas, and with least support from memory services. These effects may be prevented or reversed by post-diagnostic care.",

keywords = "cohort study, COVID-19, dementia, inequalities, inequities, post-diagnostic care, quality of life",

author = "Ben Hicks and Sanna Read and Bo Hu and Raphael Wittenberg and Amanda Grahamslaw and Anomita Karim and Evelyn Martin and Eleanor Nuzum and Jacob Reichental and Alice Russell and Elaine Siddle and Bryony Storey and Eva Tipping and Kate Baxter and Yvonne Birks and Carol Brayne and Nicola Brimblecombe and Margaret Dangoor and Josie Dixon and Kate Gridley and Harris, \{Peter R.\} and Martin Knapp and Eleanor Miles and Rotem Perach and Louise Robinson and Jennifer Rusted and Rob Stewart and Thomas, \{Alan J.\} and Sube Banerjee",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors. Alzheimer's \& Dementia: Diagnosis, Assessment \& Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association.",

year = "2022",

doi = "10.1002/trc2.12236",

language = "English",

volume = "8",

journal = "Alzheimer's and Dementia: Translational Research and Clinical Interventions",

issn = "2352-8737",

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Hicks, B, Read, S, Hu, B, Wittenberg, R, Grahamslaw, A, Karim, A, Martin, E, Nuzum, E, Reichental, J, Russell, A, Siddle, E, Storey, B, Tipping, E, Baxter, K, Birks, Y, Brayne, C, Brimblecombe, N, Dangoor, M, Dixon, J, Gridley, K, Harris, PR, Knapp, M, Miles, E, Perach, R, Robinson, L, Rusted, J, Stewart, R, Thomas, AJ & Banerjee, S 2022, 'A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 8, no. 1, e12236. https://doi.org/10.1002/trc2.12236

TY - JOUR

T1 - A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers

AU - Hicks, Ben

AU - Read, Sanna

AU - Hu, Bo

AU - Wittenberg, Raphael

AU - Grahamslaw, Amanda

AU - Karim, Anomita

AU - Martin, Evelyn

AU - Nuzum, Eleanor

AU - Reichental, Jacob

AU - Russell, Alice

AU - Siddle, Elaine

AU - Storey, Bryony

AU - Tipping, Eva

AU - Baxter, Kate

AU - Birks, Yvonne

AU - Brayne, Carol

AU - Brimblecombe, Nicola

AU - Dangoor, Margaret

AU - Dixon, Josie

AU - Gridley, Kate

AU - Harris, Peter R.

AU - Knapp, Martin

AU - Miles, Eleanor

AU - Perach, Rotem

AU - Robinson, Louise

AU - Rusted, Jennifer

AU - Stewart, Rob

AU - Thomas, Alan J.

AU - Banerjee, Sube

PY - 2022

Y1 - 2022

N2 - Introduction: COVID-19 has impacted people with dementia and their family carers, yet little is known about effects on overall quality of life. Methods: In a UK cohort study, pre- and post-pandemic data were collected from 114 carers and 93 recently diagnosed people with dementia. Latent growth curve modeling examined change in quality of life. Results: Carers reported significant decline in quality of life, although no change was demonstrated by people with dementia. In multivariable analyses, higher levels of cognitive impairment, deprivation, study site, and lower number of memory clinic contacts were associated with greater decline in carer quality of life. Discussion: Maintaining life quality for people with dementia during the pandemic appears to have come at the expense of their family carers. This inequity has fallen hardest on those caring for people with more severe dementia, in deprived areas, and with least support from memory services. These effects may be prevented or reversed by post-diagnostic care.

AB - Introduction: COVID-19 has impacted people with dementia and their family carers, yet little is known about effects on overall quality of life. Methods: In a UK cohort study, pre- and post-pandemic data were collected from 114 carers and 93 recently diagnosed people with dementia. Latent growth curve modeling examined change in quality of life. Results: Carers reported significant decline in quality of life, although no change was demonstrated by people with dementia. In multivariable analyses, higher levels of cognitive impairment, deprivation, study site, and lower number of memory clinic contacts were associated with greater decline in carer quality of life. Discussion: Maintaining life quality for people with dementia during the pandemic appears to have come at the expense of their family carers. This inequity has fallen hardest on those caring for people with more severe dementia, in deprived areas, and with least support from memory services. These effects may be prevented or reversed by post-diagnostic care.

KW - cohort study

KW - COVID-19

KW - dementia

KW - inequalities

KW - inequities

KW - post-diagnostic care

KW - quality of life

UR - https://www.scopus.com/pages/publications/85133178914

UR - https://pearl.plymouth.ac.uk/pms-research/1450/

U2 - 10.1002/trc2.12236

DO - 10.1002/trc2.12236

M3 - Article

AN - SCOPUS:85133178914

SN - 2352-8737

VL - 8

JO - Alzheimer's and Dementia: Translational Research and Clinical Interventions

JF - Alzheimer's and Dementia: Translational Research and Clinical Interventions

IS - 1

M1 - e12236

ER -

A cohort study of the impact of COVID-19 on the quality of life of people newly diagnosed with dementia and their family carers

Abstract

ASJC Scopus subject areas

Keywords

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