A Case of Clinically Diagnosed ANCA Negative Granulomatosis With Polyangiitis

A Walkden; M Salem; M Stavrakas; H Khalil

doi:10.1177/01455613211037086

A Case of Clinically Diagnosed ANCA Negative Granulomatosis With Polyangiitis

A Walkden, M Salem, M Stavrakas, H Khalil

Peninsula Medical School

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Abstract

Significance Statement Granulomatosis with polyangitis (GPA) is a systemic necrotizing vasculitis comprising of inflammation of small and medium-sized vessels. 1 It typically presents with involvement of the upper and lower airways as well as the kidneys. If left untreated, end-organ damage may occur. Hematological investigations typically demonstrate the presence of antinuclear cytoplasmic antibodies (ANCA). 2 Here, we discuss an unusual presentation of ANCA negative GPA, presenting initially with nasal symptoms.

Original language	English
Number of pages	0
Journal	Ear, Nose and Throat Journal
Volume	0
Issue number	0
Early online date	14 Sept 2021
DOIs	https://doi.org/10.1177/01455613211037086
Publication status	Published - 14 Sept 2021

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title = "A Case of Clinically Diagnosed ANCA Negative Granulomatosis With Polyangiitis",

abstract = " Significance Statement Granulomatosis with polyangitis (GPA) is a systemic necrotizing vasculitis comprising of inflammation of small and medium-sized vessels. 1 It typically presents with involvement of the upper and lower airways as well as the kidneys. If left untreated, end-organ damage may occur. Hematological investigations typically demonstrate the presence of antinuclear cytoplasmic antibodies (ANCA). 2 Here, we discuss an unusual presentation of ANCA negative GPA, presenting initially with nasal symptoms. ",

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AU - Salem, M

AU - Stavrakas, M

AU - Khalil, H

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N2 - Significance Statement Granulomatosis with polyangitis (GPA) is a systemic necrotizing vasculitis comprising of inflammation of small and medium-sized vessels. 1 It typically presents with involvement of the upper and lower airways as well as the kidneys. If left untreated, end-organ damage may occur. Hematological investigations typically demonstrate the presence of antinuclear cytoplasmic antibodies (ANCA). 2 Here, we discuss an unusual presentation of ANCA negative GPA, presenting initially with nasal symptoms.

AB - Significance Statement Granulomatosis with polyangitis (GPA) is a systemic necrotizing vasculitis comprising of inflammation of small and medium-sized vessels. 1 It typically presents with involvement of the upper and lower airways as well as the kidneys. If left untreated, end-organ damage may occur. Hematological investigations typically demonstrate the presence of antinuclear cytoplasmic antibodies (ANCA). 2 Here, we discuss an unusual presentation of ANCA negative GPA, presenting initially with nasal symptoms.

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JO - Ear, Nose and Throat Journal

JF - Ear, Nose and Throat Journal

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A Case of Clinically Diagnosed ANCA Negative Granulomatosis With Polyangiitis

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