Abstract
Systems and network biology has the potential to increase our understanding of how nutrition influences metabolic pathways and homeostasis, how this regulation is disturbed in a diet-related disease, and to what extent individual genotypes contribute to such diseases. Systems biology uses mathematical modeling and biological information to integrate all omics (nutrigenomics, transcriptomics, proteomics, metabolomics, microbiome, foodomics, and more) information levels in cells, organs, or organisms to comprehensively characterize the physiology of living organisms. The network biology analysis is of extreme interest to obtain solutions for reducing risk factors for lifestyle-related noncommunicable diseases. The revolutionary vision of systems thinking is required to understand the complexity of all types of dynamic processes in the organism as a whole.
| Original language | English |
|---|---|
| Title of host publication | Principles of Nutrigenetics and Nutrigenomics |
| Subtitle of host publication | Fundamentals of Individualized Nutrition |
| Publisher | Elsevier |
| Pages | 89-97 |
| Number of pages | 9 |
| ISBN (Electronic) | 9780128045725 |
| ISBN (Print) | 9780128045879 |
| DOIs | |
| Publication status | Published - 1 Jan 2019 |
ASJC Scopus subject areas
- General Medicine
Keywords
- Biomarkers
- Foodomics
- Metabotype
- Network biology
- Nutrigenetics
- Nutrigenomics
- Nutrimetabolomics
- Nutrimicrobiomics
- Nutriproteomics
- Nutritional systems biology
- Nutritranscriptomics
- Precision nutrition
- Systems biology
