A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.

KW Stephen; SL Creanor; JI Russell; CK Burchell; E Huntington; CF Downie

doi:10.1111/j.1600-0528.1988.tb00574.x

A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.

KW Stephen, SL Creanor, JI Russell, CK Burchell, E Huntington, CF Downie

Faculty of Health

Research output: Contribution to journal › Article › peer-review

Abstract

A 3-yr clinical trial has been conducted on 3000 12-yr-old children in Lanarkshire, Scotland, with the aim of investigating the effects on oral health of toothpastes containing both sodium monofluorophosphate and zinc citrate, the former being present at fluoride levels of 1000, 1500, and 2500 ppm F. No significant difference in caries increments was found between the group of children using toothpastes incorporating zinc citrate and their counterparts using zinc-free pastes. However, a significant anti-caries dose-response was demonstrated over the SMFP range used. This dose-response was evident for boys and girls and also for the various types of teeth and tooth surfaces.

Original language	English
Pages (from-to)	321-325
Number of pages	0
Journal	Community Dent Oral Epidemiol
Volume	16
Issue number	6
DOIs	https://doi.org/10.1111/j.1600-0528.1988.tb00574.x
Publication status	Published - Dec 1988

Keywords

Child
Citrates
Citric Acid
Clinical Trials as Topic
DMF Index
Dental Caries
Dentifrices
Dose-Response Relationship
Drug
Double-Blind Method
Female
Fluorides
Humans
Male
Phosphates
Prospective Studies
Random Allocation
Tooth

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10.1111/j.1600-0528.1988.tb00574.x

Cite this

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title = "A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.",

abstract = "A 3-yr clinical trial has been conducted on 3000 12-yr-old children in Lanarkshire, Scotland, with the aim of investigating the effects on oral health of toothpastes containing both sodium monofluorophosphate and zinc citrate, the former being present at fluoride levels of 1000, 1500, and 2500 ppm F. No significant difference in caries increments was found between the group of children using toothpastes incorporating zinc citrate and their counterparts using zinc-free pastes. However, a significant anti-caries dose-response was demonstrated over the SMFP range used. This dose-response was evident for boys and girls and also for the various types of teeth and tooth surfaces.",

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author = "KW Stephen and SL Creanor and JI Russell and CK Burchell and E Huntington and CF Downie",

year = "1988",

month = dec,

doi = "10.1111/j.1600-0528.1988.tb00574.x",

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journal = "Community Dent Oral Epidemiol",

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AU - Stephen, KW

AU - Creanor, SL

AU - Russell, JI

AU - Burchell, CK

AU - Huntington, E

AU - Downie, CF

PY - 1988/12

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N2 - A 3-yr clinical trial has been conducted on 3000 12-yr-old children in Lanarkshire, Scotland, with the aim of investigating the effects on oral health of toothpastes containing both sodium monofluorophosphate and zinc citrate, the former being present at fluoride levels of 1000, 1500, and 2500 ppm F. No significant difference in caries increments was found between the group of children using toothpastes incorporating zinc citrate and their counterparts using zinc-free pastes. However, a significant anti-caries dose-response was demonstrated over the SMFP range used. This dose-response was evident for boys and girls and also for the various types of teeth and tooth surfaces.

AB - A 3-yr clinical trial has been conducted on 3000 12-yr-old children in Lanarkshire, Scotland, with the aim of investigating the effects on oral health of toothpastes containing both sodium monofluorophosphate and zinc citrate, the former being present at fluoride levels of 1000, 1500, and 2500 ppm F. No significant difference in caries increments was found between the group of children using toothpastes incorporating zinc citrate and their counterparts using zinc-free pastes. However, a significant anti-caries dose-response was demonstrated over the SMFP range used. This dose-response was evident for boys and girls and also for the various types of teeth and tooth surfaces.

KW - Child

KW - Citrates

KW - Citric Acid

KW - Clinical Trials as Topic

KW - DMF Index

KW - Dental Caries

KW - Dentifrices

KW - Dose-Response Relationship

KW - Drug

KW - Double-Blind Method

KW - Female

KW - Fluorides

KW - Humans

KW - Male

KW - Phosphates

KW - Prospective Studies

KW - Random Allocation

KW - Tooth

U2 - 10.1111/j.1600-0528.1988.tb00574.x

DO - 10.1111/j.1600-0528.1988.tb00574.x

M3 - Article

SN - 0301-5661

VL - 16

SP - 321

EP - 325

JO - Community Dent Oral Epidemiol

JF - Community Dent Oral Epidemiol

IS - 6

ER -

A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.

Abstract

Keywords

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