Overview
Profile summary
I am a Consultant in anaesthesia and perioperative medicine at Derriford hospital. My main research interests are around transplantation and haemorrhage/coagulation, in particular how we can optimise management in these settings to improve patient outcomes.
Within transplantation I am running the NIHR-funded Octreotide randomised controlled trial. This multicentre trial is investigating whether octreotide leads to improvements in patient and liver graft outcomes following liver transplantation. We are close to completing recruitment to this trial and will be seeking further funding to expand this study in the near future. Other areas of research in transplantation that we are developing include the implementation of Prehabilitation in renal transplantation through exercise, nutrition and other forms of optimisation to improve outcomes for patients before and after transplant surgery. We are also exploring whether interventions to improve patient and organ preconditioning around transplantation reduce the risks from ischaemia reperfusion injury.
My other area of interest, coagulation, is focussed on meta-analysis and systematic review to determine optimum management of patients with, or at risk of, haemorrhage. I also hold a grant looking at coagulation changes in severe chest sepsis using thromboelastography in the intensive care unit.
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Association Between Higher Intraoperative Oxygen Exposure and Worse Patient and Organ Outcomes in Liver Transplantation
Fabes, J., Milne, A., Wells, M., Sarna, A., Neun, M. & Spiro, M., 1 Apr 2025, In: Experimental and Clinical Transplantation. 23, 4, p. 269-277 9 p.Research output: Contribution to journal › Article › peer-review
-
Plymfit study: A study to investigate the feasibility of wrist-worn smartwatch use in perioperative care [version 1; peer review: awaiting peer review]
Hunter, A. & Fabes, J., 25 Mar 2025, In: F1000Research.Research output: Contribution to journal › Article
Open AccessFile5 Downloads (Pure) -
Effect of skin tone on the accuracy of the estimation of arterial oxygen saturation by pulse oximetry: a systematic review
Martin, D., Johns, C., Sorrell, L., Healy, E., Phull, M., Olusanya, S., Peters, M. & Fabes, J., May 2024, In: British Journal of Anaesthesia. 132, 5, p. 945-956 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile34 Downloads (Pure) -
Fast-track extubation after orthotopic liver transplant associates with reduced incidence of acute kidney injury and renal replacement therapy: A propensity-matched analysis
Fabes, J., Wells, G., Abdi, Z., Bhatia, R., Muehlschlegel, P., Fortune-Ely, M., Krzanicki, D., Rahman, S. & Spiro, M., Feb 2023, In: Journal of Liver Transplantation. 9, 0Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Downloads (Pure) -
Goal-Directed Haemodynamic Therapy Improves Patient Outcomes in Kidney Transplantation
Fabes, J., Al, M. A., Sarna, A., Hadi, D., Naji, S., Banga, N., Jones, G., Berry, P. & Wittenberg, M., Jun 2023, In: Progress in Transplantation. 33, 2, p. 150-155Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure)