Projects per year
Overview
Profile summary
I am a Consultant in anaesthesia and perioperative medicine at Derriford hospital. My main research interests are around transplantation and haemorrhage/coagulation, in particular how we can optimise management in these settings to improve patient outcomes.
Within transplantation I am running the NIHR-funded Octreotide randomised controlled trial. This multicentre trial is investigating whether octreotide leads to improvements in patient and liver graft outcomes following liver transplantation. We are close to completing recruitment to this trial and will be seeking further funding to expand this study in the near future. Other areas of research in transplantation that we are developing include the implementation of Prehabilitation in renal transplantation through exercise, nutrition and other forms of optimisation to improve outcomes for patients before and after transplant surgery. We are also exploring whether interventions to improve patient and organ preconditioning around transplantation reduce the risks from ischaemia reperfusion injury.
My other area of interest, coagulation, is focussed on meta-analysis and systematic review to determine optimum management of patients with, or at risk of, haemorrhage. I also hold a grant looking at coagulation changes in severe chest sepsis using thromboelastography in the intensive care unit.
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Collaborations and top research areas from the last five years
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Perioperative Care in Renal Transplantation
Fabes, J. (PI - Principal Investigator), Mcphail, S. (PI - Principal Investigator) & Birch, F. (PI - Principal Investigator)
1/04/25 → …
Project: Research
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Perioperative Optimisation
Fabes, J. (PI - Principal Investigator) & Hunter, A. (PI - Principal Investigator)
NIHR Southampton Biomedical Research Centre, National Institute of Academic Anaesthesia
Project: Research
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A national UK-wide survey of tranexamic acid use in vascular surgery
Atha, K., Shah, A., Fabes, J. & Bera, K., 27 Feb 2026, In: Journal of Vascular Societies Great Britain & Ireland. 5, 2, p. 77-84Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A review of enhanced recovery after surgery in kidney and liver transplantation and outline of the Newcastle ERAS protocols
Bonner, E., Scuffell, C., Dowen, F., MacDougall, L., Fabes, J., Manas, D. M. & Amer, A., 28 May 2026, In: Frontiers in Transplantation. 5, 1704028.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Downloads (Pure) -
Ischaemic conditioning to improve patient and organ outcomes after kidney transplantation
Stabler, R., McKenna, H., Gimzewska, M., Harvey, D., Khurram, M. A., Mccafferty, K., Veighey, K. & Fabes, J., 4 Jun 2026, In: Cochrane Database Syst Rev. 6, 6, p. CD016342Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Understanding recruitment to a randomised controlled trial (RCT) during liver transplantation: an observational mixed-methods Study Within A Trial (SWAT)
Coppack, K. E. S., Kantsedikas, I., Brodkin, E., Loh, E. N., Ambler, G., Moonesinghe, S. R., Fabes, J., Hannon, V., Spiro, M. & Wagstaff, D., 7 Jan 2026, In: BMJ Open. 16, 1, e104310.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Association Between Higher Intraoperative Oxygen Exposure and Worse Patient and Organ Outcomes in Liver Transplantation
Fabes, J., Milne, A., Wells, M., Sarna, A., Neun, M. & Spiro, M., 1 Apr 2025, In: Experimental and Clinical Transplantation. 23, 4, p. 269-277 9 p.Research output: Contribution to journal › Article › peer-review