Overview
Profile summary
I joined the Peninsula Medical School as a Lecturer in Biomedical Sciences in May 2022. I obtained my PhD from the Institute of Child Health at University College London, where I investigated the recognition of Campylobacter jejuni lipooligosaccharide and flagella by pattern recognition receptors on dendritic cells. Following this, I undertook postdoctoral research at the Max Planck Institute for Infection Biology in Berlin, focusing on regulated macrophage cell death during immune responses in Drosophila melanogaster.
My current research explores the regulation of RNA in macrophages and glial cells in response to oxidative and proteotoxic stress. These stress responses can initiate inflammation, which plays a dual role: supporting host defense during acute infection while potentially contributing to disease pathogenesis in chronic inflammatory conditions, such as neurodegeneration and cancer.
Teaching interests
My primary teaching focus is in Infection and Immunity. Within the BMBS programme at the Peninsula Medical School I hold a number of key educational roles, including:
- Discipline Co-Lead for Immunology
- Lead for 'Doctor as Educator' Student-Selected Unit (Year 2)
- Co-Lead for 'MED003: Learning Skills and Professional Development for Medicine' module (Year 0)
- Interprofessional Learning Facilitator (Year 1)
- Enquiry-Based Learning Facilitator (Year 0)
- Student-Selected Component 1 Facilitator (Year 1)
- Academic Tutor (Years 0, 1, and 2)
In addition to my work on the BMBS programme, I also contribute to teaching on the Physician Associate Studies and Dental Therapy & Hygiene programmes.
My scholarship interests focus on advancing medical education through improved strategies for teaching teamwork skills and exploring how interactive, student-centred learning formats can enhance engagement and educational outcomes.
Supervised research degrees
Current postgraduate research supervision:
- Guy Austin – Director of Studies (October 2024 – present)
- Jules Plant – Third Supervisor (April 2025 – present)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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Collaborations and top research areas from the last five years
Research output
- 11 Article
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Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota
Stephenson, H. N., Streeck, R., Grüblinger, F., Goosmann, C. & Herzig, A., 15 Sept 2022, In: Development. 149, 18Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
Pseudaminic Acid on Campylobacter jejuni Flagella Modulates Dendritic Cell IL-10 Expression via Siglec-10 Receptor: A Novel Flagellin-Host Interaction
Stephenson, H. N., Mills, D. C., Jones, H., Milioris, E., Copland, A., Dorrell, N., Wren, B. W., Crocker, P. R., Escors, D. & Bajaj-Elliott, M., 1 Nov 2014, In: The Journal of Infectious Diseases. 210, 9, p. 1487-1498Research output: Contribution to journal › Article › peer-review
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Campylobacter jejuni Lipooligosaccharide Sialylation, Phosphorylation, and Amide/Ester Linkage Modifications Fine-tune Human Toll-like Receptor 4 Activation
Stephenson, H. N., John, C. M., Naz, N., Gundogdu, O., Dorrell, N., Wren, B. W., Jarvis, G. A. & Bajaj-Elliott, M., Jul 2013, In: Journal of Biological Chemistry. 288, 27, p. 19661-19672Research output: Contribution to journal › Article › peer-review
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Beyond lectures: leveraging competition, peer discussion and real-world scenarios in a digital card game to enhance learning of microbiology and immunology concepts
Dillon, M., Edwards, J., Hughes, A. & Stephenson, H., 13 Feb 2025, In: Access Microbiology. 7, 2, 000900.v3.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome
Barrow, E. R., Valionyte, E., Baxter, C. R., Yang, Y., Herath, S., O'Connell, W. A., Lopatecka, J., Strachan, A., Woznica, W., Stephenson, H. N., Fejer, G., Sharma, V., Lu, B. & Luo, S., 26 Mar 2024, In: Cell Reports. 43, 3, 113935.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Downloads (Pure)
Datasets
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2024 Beyond lectures micro-immune battles evaluation. Project Dataset.
Dillon, M. (Creator), Edwards, J. (Contributor), Hughes, A. (Contributor) & Stephenson, H. (Contributor), University of Plymouth, 8 Jul 2024
DOI: 10.24382/b29cf5d6-3b73-4909-a942-c9793f269667, https://pearl.plymouth.ac.uk/foh-datasets/14/
Dataset
File