Overview
Profile summary
Research Fellow in Natural Product Discovery on the Newton Fund/MRC/SAMRC - South Africa-UK Antibiotic Accelerator https://www.plymouth.ac.uk/news/uk-nil-south-africa-research-team-to-establish-hub-for-discovery-of-new-antibioticswith Prof. Mathew Upton of the Antibiotic resistant pathogens research group https://www.plymouth.ac.uk/research/biomedical-research-group/antibiotic-resistant-pathogens-research-group.This research project in Marine biodiscovery forms part of an exciting initiative between the United Kingdom and South African Medical Research Councils', with the principle aim of setting up an SA-UK Antibiotic Accelerator Initiative or Discovery Hub; particularly, investigating SA, UK, and Polar marine environments for novel antimicrobials.
Prior to taking up this position at the University of Plymouth, I did a short-term postdoctoral research fellowship on the SA-leg of the project, working with Prof. Rosemary Dorrington at Rhodes University (Marine Natural Products), whilst being seconded to CPUT, with Dr Marilize Le Roes-Hill at the Applied Microbial and Health Biotechnology Institute (Actinobacterial Research).
Professional memberships
- British Society for Antimicrobial Chemotherapy (2021)
- Applied Microbiology International (2021)
- Microbiology Society (2021)
Teaching interests
During my postgraduate studies I previously held a position as Biotechnology tutor and practical demonstrator. My duties consisted of assisting students and practical co-ordinators during practical sessions and included scientific writing, conceptualisation, and communication; tutoring, marking of tests, assignments, and examinations; and invigilating tests and examinations.
The modules I tutored were: Introduction to Microbiology (BTN 211), Quantitative Methods in Biotechnology (BTN 215), Environmental and Food Microbiology (BTN 213), Industrial and Environmental Biotechnology (BTN 312) and Plant Biotechnology and Proteomics (BTN 324).
Additional information
Research interests:
My interests include marine genetic resources, marine biodiscovery, novel antimicrobials, and antimicrobial resistance. In my postdoctoral project, I will be exploring biodiversity-rich marine environments to combat the pressing need for new antibiotics to treat antimicrobial-resistant pathogens, funded by the Newton Fund/MRC/SAMRC - South Africa-UK Antibiotic Accelerator Initiative.
During my PhD, I worked on previously unexploited Antarctic deep-sea sediments to discover novel species of marine bacteria that could possess new antimicrobials against multidrug-resistant pathogens.
In my MSc, I investigated endemic species of seaweed from South Africa for sulphated polysaccharides including fucoidan and determined their therapeutic potential including anticancer activity in vitro.
Invited lectures:
- From deep-sea exploration to deep sequencing: The lost world of bioactive compounds. EMBRIC Transnational Access program. 15th January 2019. DSMZ, Brunswick, Germany.
- Marine genetic resources in South Africa – current status, challenges, and ideas to build for the future. “Marine Genetic Resources in areas beyond national jurisdiction: bridging policy, law, science and research and development” Workshop in Brussels, 22nd May 2019, EU Commission - DG MARE, Brussels, Belgium.
- From deep-sea exploration to deep sequencing: The lost world of bioactive. XVI International Symposium on Marine Natural Products (MANAPRO) and XI European Congress on Marine Natural Products (ECMNP). September, 2019. Peniche, Portugal.
- Marine genetic resources in South Africa – current status, challenges, and ideas to build for the future. Paris Biodiversity beyond national jurisdiction (BBNJ) Workshop, 8th November 2019. Paris, France.
- Exploitation of new strains for drug discovery from Antarctica deep-sea sediments. Seminar series (MNF-bioc-374) – GEOMAR BIOTECH, 18th November 2019. University of Kiel, Kiel, Germany.
- Access and Benefit Sharing of Marine Genetic Resources. Seminar series (MNF-bioc-374) – GEOMAR BIOTECH, 18th November 2019. University of Kiel, Kiel, Germany.
Academic qualifications
PhD Molecular Life Sciences, Seconda Università degli Studi di Napoli
… → 2020
MSc (Marine) Biotechnology, University of the Western Cape
2013 → 2015
BSc (Hons) Biotechnology, University of the Western Cape
2008 → 2012
External positions
Postdoctoral Researcher on the SA-UK Antibiotic Accelerator Initiative, Rhodes University
Jul 2020 → Oct 2020
EU Commission Marie Skłodowska-Curie Actions (MSCA) PhD fellow, National Research Council of Italy
Mar 2017 → May 2020
Manufacturing Scientist, Roche Sequencing Solutions
Jan 2016 → Mar 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 14 Life Below Water
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SDG 15 Life on Land
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Collaborations and top research areas from the last five years
Research output
- 8 Article
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Impact of growth conditions on the abundance and diversity of cultivable bacteria recovered from Pheronema carpenteri and investigation of their antimicrobial potential
Conway, J., January, G. G., Muddiman, K. J., Dorrington, R., Howell, K. L. & Upton, M., 7 Nov 2025, In: FEMS Microbes. 6, xtaf016.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Psychrotrophic Antarctic marine bacteria as potential reservoirs for novel antimicrobial genes
Hwengwere, K., January, G. G., Howell, K. L., Peck, L. S., Upton, M. & Clark, M. S., 15 Apr 2025, In: FEMS Microbes. 6, xtaf004.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate Lacinutrix shetlandiensis sp. nov. WUR7
Vitale, G. A., January, G. G., Oppong-Danquah, E., Della, S. G., Palma, E. F., Tasdemir, D. & de, P. D., 3 Jul 2023, In: PNAS Nexus. 2, 7Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Downloads (Pure) -
Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential
Hesketh-Best, P. J., January, G. G., Koch, M. J., Warburton, P. J., Howell, K. L. & Upton, M., 22 Feb 2023, In: FEMS Microbes. 0, 0Research output: Contribution to journal › Article › peer-review
Open AccessFile98 Downloads (Pure) -
Genomics–Metabolomics Profiling Disclosed Marine Vibrio spartinae 3.6 as a Producer of a New Branched Side Chain Prodigiosin
Vitale, G. A., Sciarretta, M., Palma, E. F., January, G. G., Giaccio, M., Bunk, B., Spröer, C., Bajerski, F., Power, D., Festa, C., Monti, M. C., D’Auria, M. & de, P. D., 22 May 2020, In: Journal of Natural Products. 83, 5, p. 1495-1504Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Downloads (Pure)
Media stories
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New Antimicrobials Study Findings Have Been Reported by Researchers at University of Plymouth (Impact of growth conditions on the abundance and diversity of cultivable bacteria recovered from Pheronema carpenteri and investigation of their ...)
Howell, K., Upton, M., January, G. & Muddiman, K.
17/12/25
1 item of Media coverage
Media story