Overview
Organisation profile
Research in the School of Biomedical Sciences is underpinned by strong expertise in a broad range of traditional disciplines, including molecular and cellular biology, biochemistry, genetics, microbiology, immunology, virology, bioinformatics, proteomics, mitochondrial biology, physiology, nutrition and exercise. Driven by both curiosity and the general desire to improve human health, we collaborate widely to translate our basic discoveries. Such translation benefits not only from access to excellent laboratory facilities across the University, but also from tight links with colleagues in engineering, environmental science, medicine, dentistry dietetics, and the NHS. We have founded several spin-off companies that capitalise on the commercial potential of our research. Current projects include development of antimicrobials, vaccines, water quality tests, cancer diagnostics and anti-sarcopenic food supplements.
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Collaborations and top research areas from the last five years
Profiles
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Dr Charles Affourtit
- School of Biomedical Sciences - Associate Head of School - Research, Associate Professor in Mitochondrial Biology
Person: Academic (Research)
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SMART Agritech Cornwall
Metcalfe-Tyrrell, Y. (CoI - Co-Investigator), Rihan, H. (PI - Principal Investigator), Preziosi, R. (CoI - Co-Investigator) & McCallum, L. (CoI - Co-Investigator)
Cornwall and Isles of Scilly Good Growth
1/10/23 → 31/03/25
Project: Research
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Pet Ectoparasiticides: A multidisciplinary investigation into environmental, animal and public health and deep dive into use practices
Herborn, K. (PI - Principal Investigator), Ward, K. (CoI - Co-Investigator), Kelly, C. (CoI - Co-Investigator), Fitzsimons, M. (CoI - Co-Investigator), Handy, R. (CoI - Co-Investigator), Whiteside, M. (CoI - Co-Investigator), Foey, A. (CoI - Co-Investigator) & Lead, J. (CoI - Co-Investigator)
8/12/25 → 31/03/26
Project: Consultancy
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Developing a complex in vitro airway model to study respiratory viral pathogenesis, lung macrophage function and herpesviral vaccine vectors in pigs
Fejer, G. (PI - Principal Investigator)
1/07/24 → 31/03/26
Project: Research
Research output
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A Pilot Study Assessing the Oral Microbiome in Women of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play a Role?
Muddiman, K., Doble, A., Stephen, A., Bescos Garcia, R., Illsley, C., Nicholas, T., Hanks, S., du Toit, L. & Brookes, Z., Jun 2026, In: International Dental Journal. 76, 3, 109518.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Lung epithelial and alveolar macrophage-like cell interactions significantly modify innate responses to bacterial endotoxin with the involvement of direct cellular contacts, TNF-α, ICAM1 and MCP-1
Wood, C., Khera, S., Woo, M., Sharma, V., Lopatecka, J., Coulon, F., Nasir, Z., Delorme, V., Jackson, S. K. & Fejer, G., 9 Jan 2026, In: Frontiers in Immunology. 16, 1715943.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Periodontal Disease and Its Association with Porphyromonas gingivalis: Current Understanding of Microbial Dysbiosis, Immunopathology and Immune Evasion
Robins, S., Strachan, A., Salih, V. & Foey, A., 12 Mar 2026, In: Microorganisms. 14, 3, 641.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Downloads (Pure)
Press/Media
Datasets
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Biomarkers in coronary artery disease: systematic review and meta-analysis
King, N. (Creator), Smart, N. A. (Creator), Bungon, T. (Creator), Peacock, M. (Creator) & Awan, S. A. (Creator), Taylor & Francis, 2025
DOI: 10.6084/m9.figshare.28211466, https://pearl.plymouth.ac.uk/fose-datasets/64/
Dataset
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Optimization of sniff nasal inspiratory pressure (SNIP) measurement methodology in healthy subjects
Wilding, R. J. (Creator), Thynne, M. (Creator) & Subhan, M. M. F. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.6586430.v1, https://springernature.figshare.com/collections/Optimization_of_sniff_nasal_inspiratory_pressure_SNIP_measurement_methodology_in_healthy_subjects/6586430/1
Dataset
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Data associated with the manuscript Superiority of chromosomal compared to plasmid-encoded compensatory mutations.
Wright, R. C. T. (Contributor), Wood, A. J. (Contributor), Bottery, M. J. (Contributor), Muddiman, K. J. (Contributor), Paterson, S. (Contributor), Harrison, E. (Contributor), Brockhurst, M. A. (Contributor) & Hall, J. P. J. (Contributor), University of Liverpool, 2024
DOI: 10.17638/datacat.liverpool.ac.uk/2585
Dataset
Student theses
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Analysing M. abscessus-macrophage interactions and investigating treatments for M. abscessus and S. aureus intracellular bacterial infections, using a continuously growing, primary cell model of lung alveolar macrophages
Kelly, S. (Author), Fejer, G. (Director of Studies (First Supervisor)), Cox, J. (Other Supervisor), Upton, M. (Other Supervisor) & Jackson, S. (Other Supervisor), 2023Student thesis: ResM
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An assessment of the dietary bioavailability of TiO2 and inorganically carbon-based nanomaterials in rainbow trout, using the ex vivo gut sac technique and a in chemico digestibility assay
McHardy, C. (Author), Handy, R. (Director of Studies (First Supervisor)), Clark, N. (Other Supervisor) & Clough, R. (Other Supervisor), 2025Student thesis: ResM
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An Investigation for Genetic Susceptibility to Type 1 Diabetes Mellitus and its Microvascular Complications
Hegazy, D. M. (Author), 2004Student thesis: PhD
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